ObjectiveTo assess the value of percutaneous nephrostomy under ultrasound guidance for cystostomy in high-risk patients. MethodsSeventeen high-risk patients underwent the cystostomy using percutaneous nephrostomy under ultrasound guidance. The successful puncture rate, operation time, efficacy and postoperative complications were observed. ResultsThe puncture was successfully with one try in all the 17 cases, and the procedures were completed within 15 min. It is not necessary to suture the incision in the lower abdomen and the patients had slight pain during the procedure. During the 3-5 days follow-up, we did not found urecchysis around the catheter nor incision infection. ConclusionPercutaneous nephrostomy under ultrasound guidance can reduce the risk in high-risk patients receiving cystostomy.