Microsurgical treatment of spinal cord hemangioblastoma: an analysis of long term prognosis
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Supported by Research Project of Shanghai Science and Technology Committee(11DZ192130D).

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    Abstract:

    Objective To discuss the diagnosis, treatment and long term prognosis of the spinal hemangioblastoma. Methods The clinical data of 33 spinal hemangioblastoma cases, verified by microsurgeries and pathological results, were retrospectively analyzed. Twenty-four of them were males and nine were females. The magnetic resonance imaging(MRI)showed that the 33 cases included 1 medulla-cervical hemangioblastoma, 9 cervical hemangioblastomas, 2 cervical-thoracic hemangioblastomas, 16 thoracic hemangioblastomas, 1 thoracic-lumbar hemangioblastoma, and 4 lumbar hemangioblastomas. Results Total removal of hemangioblastomas was achieved in 32 patients and subtotal removal in 1, with no operation associated death. Post-operative follow-up period ranged from 16 months to 12 years. According to the McCormick scale, the functional outcomes were verified as 15(45.5%) improved, 14(42.4%) unchanged, and 4(12.1%) deteriorated. According to the Klekamp-Samii score, the functional outcomes were verified as 24(72.7%) improved, 5(15.2%) unchanged, and 4(12.1%) deteriorated. Fisher’s exact test showed that the pre-operation neuronal function was significantly associated with the prognosis (P=0.033). Conclusion Spinal hemangioblastomas are highly vascularized benign tumors, and should be resected early when the symptoms or signs present. Microsurgery is the prior protocol of treatment, and the prognosis after microsurgery is generally fine. Post-operative functional status is determined by pre-operation functional status. Klekamp-Samii score system is more suitable for the functional evaluation of spinal hemangioblastoma.

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History
  • Received:May 06,2013
  • Revised:September 23,2013
  • Adopted:September 29,2013
  • Online: October 22,2013
  • Published:
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