Recurrence rate and its risk factors after myomectomy in Chinese women:a systematic review and meta-analysis
CSTR:
Author:
Affiliation:

Department of Nutrition and Food Hygiene,School of Public Health and Management,Chongqing Medical University,Department of Epidemiology,School of Public Health and Management,Chongqing Medical University,Department of Epidemiology,School of Public Health and Management,Chongqing Medical University

Clc Number:

Fund Project:

  • Article
  • |
  • Figures
  • |
  • Metrics
  • |
  • Reference
  • |
  • Related
  • |
  • Cited by
  • |
  • Materials
  • |
  • Comments
    Abstract:

    Objective To systematically review the incidence and risk factors of recurrence after myomectomy in Chinese women, so as to provide references for creating clinical prevention strategy. Methods Relevant literatures were searched in PubMed, Web of Science, CNKI, CBM, VIP and Wanfang Databases. Eligible studies were selected according to the predefined inclusion and exclusion criteria. Then the quality evaluation (NOS) and data extraction were conducted. Meta-analysis and publication bias examination were done using software Stata11.0. Results A total of 25 studies were included at last, including 4 900 patients and 1 331 recurrent cases. The results of the meta-analysis showed that the recurrence incidence after myomectomy was 27% in Chinese women. It was found that menarche age<14y, times of pregnancy(0), fibroid number≥2, and family history of uterine myoma had the pooled RR (95% CI) values as 1.30(1.10,1.53), 1.27(1.12,1.45), 2.41(1.71,3.40), and 1.32(1.09,1.59), respectively. Conclusion The recurrence rate after myomectomy is relatively high in Chinese women. Menarche age <14 y, no preoperative history of pregnancy, fibroid number ≥2, and family history of uterine myoma are positively related to recurrence after myomectomy, and early prevention measures should be taken accordingly.

    Reference
    Related
    Cited by
Related Videos

Share
Article Metrics
  • Abstract:
  • PDF:
  • HTML:
  • Cited by:
History
  • Received:April 10,2014
  • Revised:July 10,2014
  • Adopted:July 27,2014
  • Online: September 22,2014
  • Published:
Article QR Code