Relationship between metabolic syndrome and bone mineral density in the elderly aged over 60 years in Shanghai
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Department of Endocrinology, Changzheng Hospital,Department of Endocrinology,Shidong Hospital,Department of Endocrinology,Shidong Hospital,Department of Endocrinology,Shidong Hospital,Department of Endocrinology,Shidong Hospital,Department of Endocrinology,Changzheng Hospital

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    Abstract:

    Objective To investigate the relationship between metabolic syndrome (MS) and bone mineral density(BMD) in the aged. Methods 1002 cases were divided into MS group and non-MS(NMS)group according to with or without MS. Height, weight, waist circumference and blood pressure were measured, body mass index(BMI) were calculated, total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C) ,fasting blood glucose (FBG)were tested. The calcaneal bone mineral density (BMD) was measured by the quantitative ultrasonography. To find the differences of BMD between subjects with or without MS by using the covariance analysis and to analyze the risk factors associated with BMD. Results Compared to NMS group, the values of BMI、waist circumference、TC、TG、FPG were significantly increased in MS group(P<0.05或P<0.01).Those with MS had higher BMD than those without after adjustment for age and BMI(P<0.01). There was no significant difference in BMD among patients with different number of the components of the metabolic syndrome (P<0.05). However,the difference were significant after adjustment for age and BMI(P<0.05).The multiple stepwise regression analysis demonstrated that BMD were correlated with age、waist circumference and HDL-C(P<0.05).Conclusion .The BMD is higher in aged MS patients than that in non-MS subjects.

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History
  • Received:January 14,2015
  • Revised:April 14,2015
  • Adopted:April 29,2015
  • Online: August 21,2015
  • Published:
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