Objective To investigate the epidemiology and causes of skin diseases in soldiers stationed in south-east coastal areas of China, and to put forward measures for prevention and treatment. Methods Multi-stage sampling including cluster sampling, stratified sampling and simple random sampling were used to select 625 soldiers stationed in the south-each coastal areas of China. They were surveyed by a questionnaire and received physical examination for skin diseases before diagnosing and prescribing. Logistic multiple regression analysis was used to analyze the relationship between skin disease and the possible causes of skin diseases. Results A total of 569 effective questionnaires were collected, and the participants ranged in age from 17-46 years old. It was found that 263(46.40%) soldiers had skin diseases, which fell into 40 types, with a total of 346 onsets, mainly including infectious skin diseases(197 onsets, 56.94%), allergodermia(80 onsets, 23.12%)and psychosomatic skin diseases(33 onsets, 9.54%).And the causes of the disease were complicated. Conclusion Skin diseases among soldiers stationed in south-east coastal areas of China are associated with the climate, environment, dress and equipment, and mental condition. More efforts should be made for a better living condition and habit, scientific military training, good knowledge of skin disease prevention, and more careful medical service to reduce skin diseases among the soldiers.