Analysis of relative factors of cerebral venous thrombosis on early diagnosis
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Cerebrovascular Disease Center, Changhai Hospital, the Second Military Medical University,,,Changhai Hospital, the Second Military Medical University,,

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Supported by Medical Guiding Project of Shanghai Science and Technology Committee (124119a8900) and Clinical Management Optimization Program for Shanghai Shenkang Hospital Development Center (SHDC2015607).

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    Abstract:

    Objective To analyze the relative factors in early diagnosis for cases with cerebral venous thrombosis(CVT). Methods The retrospective analysis of the clinical data in 95 patients with CVT from 2007.11to 2015.08 in Changhai Hospital was conducted. The patients were divided into early CVT diagnosis group(≤7 days) and delayed CVT diagnosis group (>7 days) according to their time from having symptoms to have a definite diagnosis.The clinical data was analyzed by univariate analysis and multivariate logistic regression analysis. Results 48 patients (50.5%)with early CVT diagnosis and 47(49.5%) with delayed CVT diagnosis. Univariate analysis showed that there was statistical significance of difference in age (P=0.016), the illness of pregnancy or puerperal (P=0.021), the level of plasma D-dimer (P=0.004), multiple CVT (P=0.010), hemorrhage (P=0.001) or venous infarction (P=0.023). Multivariate Logistic regression analysis showed that age (OR=4.197,95%CI=1.378~12.785;P=0.012), the level of plasma D-dimer (OR=0.896,95%CI=0.809~0.992;P=0.034),hemorrhage (OR=0.167,95%CI=0.052~0.540;P=0.003) or venous infarction(OR=0.093,95%CI=0.013~0.659;P=0.017)were the independent risk factors of early diagnosis. Conclusion Young patients, the increase of the level of plasma D-dimer, merged with hemorrhage or venous infarction are important conditions for the early diagnosis of CVT.

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History
  • Received:April 27,2016
  • Revised:September 23,2016
  • Adopted:October 12,2016
  • Online: October 24,2016
  • Published:
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