Bile acid in glucolipid metabolic diseases: an update
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Changhai Hospital,

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Supported by Exploration Program of Changhai Hospital (CH125541900)

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    Abstract:

    Bile acids, as one of the constituents of bile, can promote the digestion and absorption of fat and cholesterol metabolism. Studies find that bile acid is a signal molecule that not only combines with nuclear hormone receptors such as farnesoid X receptor, and G protein coupled bile acid receptor 5, to regulate their own metabolism, but also plays an important role in diabetes, obesity, non-alcoholic fatty liver disease and other metabolic diseases. The research on its mechanism will provide a solid theoretical basis for the diagnosis and treatment of metabolic diseases. In this review, we summarized the research progress of bile acids in glucolipid metabolic diseases.

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History
  • Received:November 15,2016
  • Revised:February 22,2017
  • Adopted:March 17,2017
  • Online: June 28,2017
  • Published:
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