Bronchopulmonary dysplasia (BPD) is one of the most serious complications of preterm infants and seriously affects the quality of life of premature infants. With the continuous improvement of neonatal intensive care technology, more and more methods were used for the treatment of BPD, but the effect is still not satisfactory and has controversies. As a routine treatment, drug therapy plays an important role in the prevention and treatment of BPD. In this paper, we summarized the research progress of commonly used clinical drugs for BPD, and proposed possible effective ways for the prevention and treatment of BPD.