Premenstrual dysphoric disorder (PMDD) is diagnosed as a type of mood disorder in the Diagnostic and Statistical Manual of Mental Disorders 5^th edition (DSM-5). In addition to depressive symptoms, PMDD can be accompanied by somatic symptoms and is characterized by cyclicity (premenstrual). The etiology and pathogenesis of PMDD are not clear, probably involving the fluctuation of estrogen, the weakened role of neurosteroids hormones, immune activation and inflammatory response, the abnormal functional activities of some brain areas (such as amygdala, prefrontal cortex), psychosocial factors, etc. There is no radical treatment for PMDD due to the unknown pathogenesis. Treatments including drugs (such as antidepressants, oral contraceptives), psychotherapy, and complementary medicines (such as traditional Chinese medicine, acupuncture) are used to relieve patients' symptoms.