Pseudohypoparathyroidism (PHP) is a group of dominant/recessive genetic diseases characterized by low calcium, high phosphorus and parathyroid hormone (PTH) resistance. The main clinical manifestations are repeated low-calcification convulsions, often accompanied by language and physical developmental delay and Albright hereditary osteodystrophy. Symptoms can be relieved after calcium supplementation. The disease is rare in clinical practice, and it is often caused by hand and foot convulsions, which often leads to misdiagnosis and missed diagnosis. This article mainly discusses the classification and mechanism of PHP, differential diagnosis, treatment and other aspects, aiming to improve the understanding of the majority of clinicians through this typical case report.