This article reviewed recent progress in non-interventional diagnosis of endometriosis, including serum and tissue markers, screening methods with genomics/proteomics and spectrum analysis, application of diagnostic scoring system and algorithm model, application of image parameters, new technologies and new operation skills in imaging diagnosis. The diagnostic efficacy, clinical feasibility and disadvantage were analyzed. Based on the current research status of endometriosis diagnosis, it is believed that a better diagnosis scoring system can provide evidence for rapid differential diagnosis, diagnostic algorithm based on multiple markers can promote diagnosis accuracy, and new imaging technologies can improve the diagnostic sensitivity and differential diagnostic ability.