Autonomic nervous dysfunction caused by circadian disruption: research progress
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Supported by National Natural Science Foundation of China (81970354), Natural Science Foundation of Shanghai (22ZR1478400), Shenlan Project of Naval Medical University (Second Military Medical University) (23TPSL0101), and Outstanding Talent Project of Naval Medical Center of Naval Medical University (Second Military Medical University) (21TPQN0801).

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    Abstract:

    Keeping the balance of autonomic nervous system function is essential to maintain the physiologic function of human body, and the circadian rhythm system is involved in the regulation of autonomic nervous system function. Circadian disruption can increase sympathetic nervous activity and decrease vagus nerve activity, thus promoting the development and progression of cardiovascular disease. However, the mechanism of autonomic nervous function imbalance caused by circadian disruption is not clear. Based on the influence of circadian rhythm on autonomic nervous function, this paper aims to clarify the possible mechanism of autonomic nervous function imbalance caused by circadian disruption, and summarizes the prevention and treatment measures such as melatonin treatment, light regulation, exercise therapy, vagus nerve stimulation, etc.

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History
  • Received:November 05,2023
  • Revised:January 18,2024
  • Adopted:
  • Online: March 29,2024
  • Published: March 20,2024
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