Post-traumatic stress disorder (PTSD) and other psychiatry disorders are highly comorbid mental health problems, such as depression disorder, anxiety disorder, sleep disorder, and personality disorder. Comorbidity is associated with negative treatment and prognosis of both diseases, and is also an important factor in the reduction of combat personnel in modern war. Mental health of military officers and soldiers has drawn wide attention owing to the complexity and diversity of military tasks in recent years. As a common psychological trauma in the battlefield environment, PTSD needs to be fully concerned in the future war. This paper discusses the research progress of comorbidities of PTSD from the aspects of epidemiological characteristics, influencing factors, related mechanisms and treatment intervention strategies, so as to provide reference for the improvement of war capacity and the clinical diagnosis and treatment of PTSD.