Supported by Clinical Research Project of Health Industry of Shanghai Municipal Health Commission (20194Y0232), Independent Scientific Research Project of Military High-Level Science and Technology Innovative Talent Program (2020QN06125), Shanghai Shuguang Talent Project, Fundamental Medical Research Project of The First Affiliated Hospital of Naval Medical University (Second Military Medical University) (2023PY17), and Changhong Talent Project of The First Affiliated Hospital of Naval Medical University (Second Military Medical University).