Objective: To investigate the relationship between constituents and pharmacological effects of Scrophularia ningpoensis (XuanSheng). Methods: The isolation and identification of compounds were done mainly by no n-polar macroreticular resin, sephadex LH-20, ODS, silica gel column chromatography and FABMS, NMR etc, spectra. Results: The inhibition of the LTB 4 f ormation in the rat abdominal neutral leukocytes by drugs isolated from S. nin gpoensis were observed. The iridoid glycosides XS-6, XS-7 showed weak action , but the phenylpropanoid glycosides XS-8, XS-10 showed potent action at the c oncentration of 0.5 mmol/L. In the inhibition of the rabbit platelet aggregation, iridoid and phenylpropanoid glycosides were active in inhibiting the rabbit threshold ADP-induced and AA-induced but not 20 nmol/L PAF-induced pl atelet aggregation at the concentration of 0.5 mmol/L in vitro. Conclusion: The phenylpropanoid and iridoid glycosides may be associated with anti-inflammation and anti-platelet aggregation effects of S. ningpoensis.