Abstract:Objective To observe the clinical effect of Guanggu Jisheng decoction on the treatment of coronavirus disease 2019 (COVID-19) during recovery stage. Methods A total of 122 convalescent COVID-19 patients in Guanggu Branch of Maternity and Child Healthcare Hospital of Hubei Province were treated with Guanggu Jisheng decoction for 3 consecutive courses, each course lasting 3 days. The changes of traditional Chinese medicine (TCM) syndromes before and after treatment were compared. Scores were recorded according to the laboratory testing and the severity of symptoms (no symptom, mild, common and severe) to investigate the clinical curative effect of Guanggu Jisheng decoction on the treatment of convalescent COVID-19. Results According to the TCM syndrome scores, after one course of treatment (3 days), the total effective rate was 75.41% (92/122), with the effective rate being 31.97% (39/122), the significant efficiency being 21.31% (26/122), and the clinical recovery rate being 22.13% (27/122). After two courses of treatment (6 days), the total effective rate was 86.89% (106/122), with the effective rate being 32.79% (40/122), the significant efficiency being 28.69% (35/122), and the clinical recovery rate being 25.41% (31/122). After three courses of treatment (9 days), the total effective rate was 88.52% (108/122), with the effective rate being 16.39% (20/122), the significant efficiency being 31.15% (38/122), and the clinical recovery rate being 40.98% (50/122). The symptoms of cough, fatigue, shortness of breath and sweating were significantly improved. No patients turned positive again from negative of respiratory pathogen nucleic acid. Conclusion Guanggu Jisheng decoction has a good clinical effect on convalescent COVID-19 patients. It can significantly improve the clinical symptoms.

Abstract:Cytokine storm, a runaway overwhelming immune response, plays an important part in the pathogenesis of coronavirus. The virus hijacks the immune system, resulting in a loss of negative feedback on the immune regulation and an overproduction of inflammatory cytokines, which subsequently impairs the pulmonary diffusion function and leads to multi-organ dysfunction. A series of progresses have been achieved in studies targeting the coronavirus cytokine storm, such as granulocyte colony-stimulating factor, tocilizumab, camostat mesylate, and blood purification treatment, which may provide effective ways to alleviate the coronavirus disease 2019 (COVID-19) epidemic. Nevertheless, further clinical verifications of the above research findings are requested due to the unique pathology of COVID-19. This paper reviews the advances in cytokine storm and immunoregulatory therapy of coronavirus pneumonia.

Abstract:Since the outbreak of the coronavirus disease 2019 (COVID-19), tens of thousands of medical staff and paramedical staff have been involved in the treatment of COVID-19 patients. Heavy personal protective equipment and continuous high-intensity work have brought great challenges to the staff. Fainting incidents occur frequently in the isolation ward. The emergency treatment after fainting is directly related to the safety and health of the injured. Based on the latest domestic and international literatures and guidelines, we proposed a first-aid procedure for staff who fainted in the isolation ward, aiming to provide reference for the treatment of staff fainting in the isolation ward.

Abstract:Objective To observe the visits of fever clinic during the epidemic of coronavirus disease 2019 (COVID-19) and the epidemic characteristics of COVID-19, so as to analyze the disease development trend. Methods The clinical data of fever outpatients (including covid-19 patients) in Gongli Hospital affiliated to Naval Medical University (Second Military Medical University) from Jan. 15, 2020 to Feb. 29, 2020 were collected for epidemiological descriptive analysis. Results Among the 2 193 patients visiting our hospital between Jan. 15, 2020 and Feb. 29, 2020, 97.08% had respiratory system infection, followed by digestive system infection and urinary system infection. Eighty-one suspected cases and 10 confirmed cases of COVID-19 were identified. Among the suspected cases, there were 38 males (46.91%) and 43 females (53.09%). Among the confirmed cases, four were males and six were females. The onset age of the suspected cases ranged from 20 to 69 years old (83.95%), and all the 10 confirmed patients were ≥ 50 years old. The suspected patients were mainly employees (31 cases, 38.27%) and retirees (14 cases, 17.28%). Among the 10 confirmed patients, eight cases were retirees. Of the suspected cases, 15 (18.52%) had lived in Hubei province and 52 (64.20%) had an epidemiological history. Of the confirmed cases, seven had lived in Hubei province and all had an epidemiological histories. The onset cycles of suspected and confirmed cases were mainly from Jan. 21, 2020 to Feb. 10, 2020. The main clinical symptoms of the suspected cases were fever (66 cases, 81.48%) and cough (50 cases, 61.73%). The blood routine showed normal white blood cell (65 cases, 80.25%), normal lymphocyte (49 cases, 60.49%) and decreased lymphocyte (24 cases, 29.63%). Chest CT showed COVID-19 characteristics in 13 cases (16.05%). Among the 10 confirmed patients, the main clinical manifestations were also fever (nine cases) and cough (eight cases). The blood routine showed normal white blood cells (10 cases), normal lymphocytes (six cases) and decreased lymphocytes (four cases). Chest CT showed COVID-19 characteristics in seven cases. Conclusion COVID-19 is more common in middle-aged and elderly retirees, with significant epidemiological and family clustering characteristics.

Abstract:Objective To explore the panic state and related influencing factors among military personnel during the early epidemic stage of coronavirus disease 2019 (COVID-19). Methods In the early stage of the COVID-19 epidemic, 431 officers and soldiers stationed in Hebei were randomly selected by the cluster sampling method and investigated with psychological stress self-evaluation test (PSET), self-rating anxiety scale, and self-designed questionnaires regarding the knowledge of COVID-19, sources of psychological panic scale, evaluation scale of various information released and risk perception scale. Results A total of 411 valid questionnaires were collected, with an effective rate of 95.36%. The results showed that 5.84% (24/411) of the officers and soldiers were in psychological stress state and 4.14% (17/411) in psychological panic state. The psychological panic score of officers and soldiers in psychological stress state (47.76±6.51) was significantly higher than that in non-stress state (32.95±10.94), and the difference was statistically significant (t=106.01, P<0.01). There were significant differences in their understanding of different dimensions of COVID-19 knowledge (χ²=91.53, P<0.01). The high proportions of lack of understanding were found for COVID-19 related research progress (22.87%, 94/411) and symptoms (20.92%, 86/411). The main sources of psychological panic were the highly infectious trait of the virus, all wearing masks and eye glasses, information from the Internet and so on. Among all kinds of released information, the numbers of cumulative confirmed cases, new confirmed cases and cumulative suspected cases were the concerned epidemic information. The age, degree of anxiety in risk perception, possibility of infection, level of psychological stress and knowledge regarding COVID-19 were the predictors of psychological panic among military personnel (P<0.05 or P<0.01). Among the dimensions of risk perception, the predictors for apprehension regarding COVID-19 among military personnel included the influence of COVID-19 on individuals and society and event characteristics of COVID-19 (P<0.05 or P<0.01). For the interventions of panic state, providing relevant medical knowledge was the most needed. Conclusion During the early stage of COVID-19 epidemic, factors such as risk perception and the sources of psychological panic can affect the psychological panic among military personnel. During the CVOID-19 epidemic, corresponding measures should be taken to prevent the psychological panic among the officers and soldiers.

Abstract:The outbreak of coronavirus disease 2019 (COVID-2019) has greatly affected the normal production and life of the society. Mental health conditions of military personnel are very important for the maintenance of the stability of the army. Based on the previous studies, this study explored the mental health problems that may occur among first-line officers and soldiers, isolated personnel and stationed officers and soldiers, analyzed their causes, and proposed the coping strategies from the perspectives of problem solving and emotion regulation.

Abstract:Objective To investigate the current status of grief counseling of clinicians from five coronavirus disease 2019 (COVID-19) designated hospitals in Wuhan and to provide reference for hospital management. Methods A total of 223 clinicians from designated hospitals were investigated with a basic information questionnaire and attitudes and skills of grief counseling scales. Results A total of 208 valid questionnaires were collected, with an effective rate of 93.3%. The score of grief counseling skills of clinicians from COVID-19 designated hospitals was 19.35±4.75, which was in the middle and lower level. Responsibilities and roles, and frequency of contacting bereaved family members had significant effects on the grief counseling skills (P<0.01). While the score of grief counseling attitudes of clinicians was 33.21±9.23, which was in the middle level. Whether they had received relevant training, the communication ability, and other grief counseling skills had significant impacts on their grief counseling attitudes (P<0.01). Conclusion The skills and attitudes of grief counseling of clinicians from COVID-19 designated hospitals in Wuhan still need to be improved. The hospital should set up a grief counseling committee, establish a complete grief guidance system and build a long-term training mechanism.

Abstract:Objective To investigate the status of grief counseling among front-line nurses in Wuhan during the coronavirus disease 2019 (COVID-19) epidemic, so as to provide reference for formulating reasonable nursing management strategies. Methods A total of 225 front-line nurses were investigated with a basic information questionnaire and attitudes and skills of grief counseling scales. Results A total of 214 valid questionnaires were collected, with an effective rate of 95.1%. The score of grief counseling attitudes of nurses was 32.80±9.41, which was in the middle level. Other grief counseling skills, communication ability, whether they had received relevant training, and frequency of contacting bereaved family members had significant impacts on nurses' grief counseling attitudes (P<0.05). The score of grief counseling skills was 19.24±4.10, which was in the lower middle level. Grief counseling, frequency of contacting bereaved family members, grief counseling training, and education background had significant impacts on nurses' grief counseling skills (P<0.05). Conclusion During the COVID-19 epidemic, there have been room for improvement in grief counseling for bereaved family members among nurses in Wuhan. It is suggested to set up a grief counseling nursing group and establish a long-term and sound training framework.

Abstract:Objective To investigate whether the low-frequency pulsed electromagnetic fields (LF-PEMFs) can enhance the osteogenic differentiation of human periodontal ligament stem cells (hPDLSCs) induced by bone morphogenetic protein 9 (BMP9). Methods We isolated CD146⁺/STRO-1⁺ cells (namely PDLSC) from periodontal ligament cells of healthy human premolars, transfected the PDLSC with BMP9-overexpressing recombinant adenoviruses (Ad-GFP-BMP9), exposed the cells to the different intensities of PEMF stimulation (15 Hz, 0.6,1.2,1.8,2.4,3.0 mT, 1 h/12 h), and then detected the expression of runt-related transcription factor 2 (Runx2), alkaline phosphatase (ALP), osteopontin (OPN) and osteocalcin (OCN) by qRT-PCR and Western blotting. Results Overexpression of BMP9 significantly promoted the expression of osteogenic markers (Runx2, ALP, OCN and OPN) in PDLSC (P<0.05). After the intervention with 1.2, 1.8, 2.4 and 3.0 mT PEMF, the expression levels of osteogenic markers in PDLSC were significantly higher than those exposed to BMP9 alone (P<0.05), and reached the peak at 2.4 mT (P<0.05), indicating that LF-PEMFs enhanced BMP9-induced osteogenic differentiation of PDLSC, and there was a "window effect". Conclusion LF-PEMFs stimulation (15 Hz, 1.8 to 3.0 mT) can enhance BMP9-induced osteogenesis of hPDLSCs in vitro.

Abstract:Objective To monitor and analyze the cardiac morphology and functional status at early stage after transcatheter aortic valve implantation (TAVI) by two-dimensional echocardiography. Methods A total of 33 patients with TAVI were selected from Dec. 2017 to Dec. 2019 in the Department of Cardiovascular Surgery of our hospital. The age, gender, New York Heart Association (NYHA) cardiac function classification, previous cardiac surgery history, Society of Thoracic Surgeons (STS) score, surgical approach, complication, other basic data, as well as echocardiography data were collected before and after TAVI (0-2 months). Results Thirty-three patients met the inclusion criteria, including 20 patients with severe aortic stenosis (SAS group), eight patients with severe aortic regurgitation (SAR group), and five patients with SAS combined with SAR (combined group). In the early postoperative period, one patient in SAS group was hospitalized twice for heart failure aggravated by arrhythmia, four patients in SAS group had tiny perivalvular leakage and one patient had large perivalvular leakage; moderate perivalvular leakage occurred in one patient in SAR group, and mild perivalvular leakage occurred in one patient in the combined group. Compared with the preoperative values, early after operation 33 cases had decreased left ventricular end-diastolic volume (LVEDV), left atrial volume (LAV), and maximum aortic valve pressure gradient (AVPG_max), increased effective aortic valve area (AVA) (all P<0.01), and unchanged left ventricular ejection fraction (LVEF), interventricular septum thickness (IVST), and posterior wall thickness (PWT) significantly (all P>0.05). In SAS group, LVEF and AVA increased, while LAV and AVPG_max decreased significantly (P<0.05 or P<0.01). In SAR group, LVEDV and LAV decreased, while IVST increased significantly (P<0.05 or P<0.01). In combined group, LVEDV, LAV and AVPG_max decreased, while AVA increased significantly (P<0.05 or P<0.01). Conclusion Early after TAVI, the cardiac remodeling and systolic function are improved to different degrees in patients with SAS, SAR, and SAS combined with SAR. High risk patients with SAR alone or combined with SAS can benefit from TAVI.

Abstract:Objective To compare different blocking methods for eliminating autofluorescence of mouse liver frozen sections, so as to find the best method to reduce the interference to immunofluorescence positive signals and improve the accuracy of immunofluorescence. Methods Intrasplenic injection-liver colonization nude mice:Hepa1-6-GFP cells were intrasplenically injected into male athymic BALB/c nude mice to create liver colonization models. Liver tissues were frozen and continuously sectioned. Sections were blocked with AB reagent (A reagent:streptavidin reagent, B reagent:biotin reagent), blocking buffer, AB reagent+blocking buffer, or acetone+AB reagent+blocking buffer, and then the autofluorescence of the frozen sections was detected. C57BL/6 mice:the liver tissues of C57BL/6 mice were frozen and continuously sectioned, and then the sections were blocked with AB reagent, blocking buffer, AB reagent+blocking buffer, or acetone+AB reagent+ blocking buffer. Liver macrophages (Kupffer cells) were labeled with F4/80, and then the autofluorescence of mouse liver frozen sections was detected. Results In the immunofluorescence staining of liver tissue frozen sections, all the above four blocking methods could reduce the autofluorescence of liver sections, and acetone+AB reagent+blocking buffer group had the best effect. Conclusion The combined buffers (acetone+AB reagent+blocking buffer) has the best effect in eliminating the autofluorescence of mouse liver frozen section.

Abstract:Cerebrovascular diseases such as intracranial atherosclerosis, intracranial aneurysm and ischemic stroke have become the important causes of death and disability. The structural and functional changes of cerebrovascular, which are caused by various pathogenic factors, are the common pathophysiological basis of cerebrovascular diseases. At present, the etiology of cerebrovascular diseases has not been clarified. Growing evidence suggests that matrix metalloproteinases play an important role in the occurrence and development of cerebrovascular diseases. Blocking or inhibiting the expression of matrix metalloproteinases provides a new theoretical basis for non-invasive treatment of cerebrovascular diseases. This review discusses the relationship between matrix metalloproteinases and cerebrovascular diseases.

Abstract:Malignant biliary obstruction (MBO) leads to obstructive jaundice as a result of bile excretion disorder, which may cause complications such as cholangitis, sepsis, hepatic failure and even life-threatening. Biliary drainage is an effective mean to relieve symptoms and improve patients' quality of life. At present, endoscopic retrograde cholangiopancreatography (ERCP) is the first-line palliative treatment for MBO patients without surgical opportunity. In recent years, endoscopic ultrasound-guided biliary drainage (EUS-BD) has been gradually accepted as an alternative to percutaneous transhepatic biliary drainage (PTBD) in MBO with failed ERCP. The available evidence suggests that EUS-BD might even replace ERCP as the first-line procedure in patients with malignant distal biliary obstruction by experienced surgeons. This paper reviews the research progresses of EUS-BD in MBO.

Abstract:In modern war, the advancement of military technology and weapons results in the gathering of severe casualties and increases the difficulty in field rescue, which brings great challenges for medical staff to complete the assessment, classification and rescue tasks in a short time. Ultrasonic examination can easily and quickly screen and diagnose the wounded in battlefield environment or field hospital, and improve the efficiency of classification and treatment. Ultrasonic visualization technology can improve the screening and diagnosis efficiency of war trauma patients with chest, abdomen, craniocerebral and skeletal soft tissue injuries. It also provides convenience for emergency treatment of war trauma patients and improves the emergency treatment effects. This paper reviews the application of ultrasonic visualization technology in the evaluation and emergency treatment of war trauma patients.

Abstract:Post-traumatic stress disorder (PTSD) is a kind of psychological disorder caused by unusual threatening or catastrophic events, and it is one of the urgent public health events in the 21^st century, which deserves more attention. Exploration of the underlying brain mechanisms of PTSD can provide theoretical basis for the early intervention, psychological nursing and follow-up treatment of PTSD. Current studies have analyzed PTSD brain functional magnetic resonance imaging at resting state and task state. The results showed that the amygdala response was enhanced in PTSD patients, and their hippocampal volume was reduced with decreased response of anterior cingulate cortex and medial prefrontal cortex. Future studies should attach greater importance to the selection of control group, with special focus on the presence of comorbidity.

Abstract:Objective To analyze the characteristics of "Mission Harmony" overseas medical services and medical consumable requisitions, so as to provide reasonable and scientific advice for preparing future "Mission Harmony" overseas medical consumables and to scientifically and reasonably design the proportions of the medical consumable for each department. Methods A retrospective analysis was made on the person times of medical services, medical consumable requisitions and distribution proportion of medical consumable for each department based on "Mission Harmony-2017" overseas medical services in eight countries and "Mission Harmony-2018" overseas medical services at 18 service sites in 10 countries. Results A total of 110 983 patients received diagnosis and treatment, 587 patients received surgical treatment, and 454 patients were hospitalized during the two missions. Department deployment before departure of the hospital ship was the peak period of medical consumable requisitions (43.80%, 241 543/551 510). The basic medical consumables were mainly applied during the overseas medical services (49.72%, 274 225/551 510). Specialized medical consumables were mainly applied during the department deployment period (11.43%, 63 046/551 510). The medical consumables were mainly applied by the General Department of the Outpatient Department (42.39%, 233 811/551 510), Operation Room (22.99%, 126 784/551 510), and the Ward (9.67%, 53 319/551 510), while Imaging Department was the main auxiliary department to apply (4.19%, 23 085/551 510). During the periods of department deployment and overseas medical services, there were significant differences in basic medical consumables and specialized medical consumables in the General Department, Stomatology Department, Ophthalmology Department, Gynecology Department, Laboratory Department, Special Examination Room, Imaging Department, Sterilization and Supply Department, Operation Room, Ward, and others (all P<0.01). During the department deployment period, the General Department, Gynecology Department, Laboratory Department, Special Examination Room, Operation Room, Ward, and others mainly applied for basic medical consumables, while Stomatology Department, Ophthalmology Department, Imaging Department and Sterilization and Supply Department mainly applied for specialized medical consumables. During the period of overseas medical services, the General Department, Stomatology Department, Ophthalmology Department, Gynecology Department, Laboratory Department, Special Examination Room, Sterilization and Supply department, Operation Room, Ward, and others mainly applied for basic medical consumables, while the Imaging Department mainly applied for specialized medical consumables. Conclusion Different departments have different requisitions on medical consumables at different task stages. It is necessary to strengthen the management of consumables and improve the pertinence of requisition and distribution of consumables. The consumption and distribution proportions of medical consumables in each department can provide reference for the preparation, requisition and distribution for future tasks.

Abstract:This paper introduces the characteristics and classification of "virtual reality (VR)" technology. Based on the "VR" training plan, training target, training stage and training mode of US army medical staff, combined with the current difficulties and challenges from the medical service work in PLA overseas base, this paper proposes some enlightenment for the construction and training of medical service force in base, so as to provide a reference for improving the medical service support capacity.

Abstract:Objective To investigate the positive rate of heparin/platelet factor 4 (H/PF4) antibody in maintenance hemodialysis (MHD) patients, and to explore its clinical significance. Methods Fifty-four MHD patients treated in the Department of Nephrology of Changzheng Hospital of Naval Medical University (Second Military Medical University) were selected. The dialysis duration (unfractionated heparin/low-molecular-weight heparin) of all patients was more than 3 months, with no infections or other active diseases. Serum samples were collected from the MHD patients before dialysis, and IgG H/PF4 antibody was detected by particle immunofiltration assay. The general condition, hemoglobin level, platelet count, anticoagulant method (unfractionated heparin/low-molecular-weight heparin), anticoagulant dosage, and dialysis mode (conventional hemodialysis/nocturnal extended hemodialysis) were compared between the H/PF4 antibody-positive group and H/PF4 antibody-negative group. After 3 years' follow-up, the change of platelets, the incidence of vascular access thrombosis, cardio-cerebral vascular events, hospitalization rates and mortality were compared between the two groups. Results The positive rate of H/PF4 antibody was 63.0% (34/54) in MHD patients. There were no significant differences in gender, age, dialysis age, hemoglobin level or platelet count between the H/PF4 antibody-positive group and H/PF4 antibody-negative group (P>0.05). The positive H/PF4 antibody was not correlated with primary kidney disease, anticoagulant method, anticoagulant dosage, or dialysis mode (all P>0.05). After 3 years' follow-up, there were no significant differences in the change of platelet, the incidence of vascular access thrombosis (14.7%[5/34] vs 25.0%[5/20]), cardiovascular events, cerebrovascular events, hospitalization rates, or mortality between the two groups (all P>0.05). Conclusion The positive rate of H/PF4 antibody is high in MHD patients. The production of H/PF4 antibody is not related to the heparin type, heparin dosage, or dialysis mode. The positive H/PF4 antibody has no significant effect on platelet counts or adverse events, including thrombosis and cardiovascular events.

Abstract:Objective To analyze the magnetic resonance imaging (MRI) features of caesarean scar pregnancy (CSP), and to evaluate the diagnosis value of MRI in CSP. Methods The MRI data of 38 patients with clinically and pathologically confirmed CSP were retrospectively analyzed. These patients aged 19 to 50 years old, with one to two previous cesarean sections. The interval between this pregnancy and the last cesarean section was 2 to 11 years, the menopause time was 32 to 90 days, the urine human chorionic gonadotrophin (HCG) were all positive, and the blood β-HCG was 159.7-210 800.0 U/L. Twenty-nine cases were treated due to a small amount of vaginal bleeding after menopause, and nine cases due to abdominal pain. Results On the sagittal T2-weighted image, 38 cases of gestational sacs were clearly showed, of which 28 cases had round or oval morphology, with low signal on T1 and high signal on T2; 10 cases of gestational sacs showed irregular mixed cystic solidity with slightly low signal on T1 and slightly high signal on T2, and the contents were significantly strengthened after the enhancement. In all cases, the cyst wall was intact and located at the scar of the cesarean section of the anterior inferior wall of the uterus. In two cases of MRI grade 0, the gestational sac was located on the scar surface and grew into the uterine cavity without involving the myometrium; in 13 cases of grade 1, the gestational sac slightly invaded the myometrium, but mainly grew in the uterine cavity, with a clear boundary between the gestational sac and the myometrium; in 14 cases of grade 2, the gestational sac was small and completely implanted into the myometrium, the endometrial junction was continuously interrupted, the anterior-inferior wall of the uterus was thin, in the shape of "W" or "U", without invading the serosa; in nine cases of grade 3, the gestational sac was large, completely implanted into the myometrium and protruded out of the uterine contour, compressing the bladder. Fifteen patients of MRI grade 0 and 1 were mainly treated with methotrexate, mifepristone or misoprostol, and/or ultrasound-guided curettage; 23 patients of grade 2 and 3 were mainly treated with curettage, excision of scar lesions and scar repair. Conclusion The typical MRI features of CSP can guide the clinical treatment decision-making, especially for the choice of operation mode.

Abstract:Objective To investigate the effects of individualism and collectivism on the self-reported health of military retired cadres. Methods The Chinese version of the European quality life-5 dimensions (EQ-5D), the individualism-collectivism scale, and the Memorial University of Newfoundland Scale of Happiness were used to survey 112 retired military cadres from military cadre sanatoria in Shanghai, Suzhou and so on. The data were analyzed by SPSS 22.0 software. Results A total of 112 questionnaires were sent out, and 71 valid questionnaires were collected, with an effective rate of 63.39%. The scores of individualism and collectivism of retired military cadres (n=71) were lower than those of college students (n=403), the difference was statistically significant (t=-4.81 and -7.95, both P<0.01). Correlation analysis results showed that there was no significant correlation between gender, age, education level, marital status, children's number, residence status and self-reported health status, subjective well-being, individualism and collectivism (all P>0.05); subjective well-being, individualism and self-reported health were positively correlated (r=0.44, P<0.01; r=0.29, P<0.05), collectivism and self-reported health were not significantly correlated (r=0.19, P>0.05), and individualism and collectivism were positively correlated (r=0.67, P<0.01). Hierarchical multiple regression showed that the inclusion of individualism and collectivism improved the model interpretation rate (ΔR²=0.08, F=3.41, P<0.05) after controlling subjective well-being. Individualism could predict health status (β=0.34, P<0.05), while collectivism could not (β=-0.09, P=0.55). Conclusion Individualistic cultural orientation is the main factor that affects the health of retired military cadres, while collectivist cultural orientation has no obvious effect.

Abstract:Objective To establish a rapid determination model based on near-infrared spectroscopy (NIRS) for glycyrrhizic acid and liquiritin in Glycyrrhizae Radix et Rhizoma Yinpian. Methods The contents of glycyrrhizic acid and liquiritin in Glycyrrhizae Radix et Rhizoma Yinpian from different places of origin were determined by high performance liquid chromatography (HPLC) as reference values. At the same time 2 200-2 049, 1 750-1 450, 1 151-1 001 nm and 1 795-1 475, 1 395-1 293, 1 125-1 030 nm wavelength ranges of near-infrared spectra were selected to establish the rapid determination model by combining partial least squares (PLS) regression analysis with cross validation method. Results The correlation coefficient and root-mean-squares error of cross validation of the established content calibration model were 0.980 and 0.184 for glycyrrhizic acid, and 0.919 and 0.144 for liquiritin, respectively. Conclusion The NIRS-PLS method is convenient, rapid and nondestructive for the content determination of glycyrrhizic acid and liquiritin for large number of Glycyrrhizae Radix et Rhizoma Yinpian, which provides a new and feasible method for the rapid quality evaluation of Glycyrrhizae Radix et Rhizoma Yinpian.

Abstract: