Recently, the theoretical system and practical path for the deep integration of digitalization and traditional industrialization have gradually matured. Medical innovation and digital technology are progressing, and the deep integration of intensive care medicine and intelligence is surpassing the traditional informatization and ushering in new development opportunities. Technologies such as 5G, big data, artificial intelligence, and digital twins can help to understand more complex critical care issues, improve the diagnoses and prediction of diseases and symptoms, develop more accurate treatment strategies, and even transform the service model of critical care medicine. This paper summarizes the application and challenge of digital technology in the practical scenarios of critical care medicine, so as to further consolidate infrastructure, enrich application scenarios, accelerate implementation, improve effectiveness, and strengthen the safety and compliance with the regulations.