| 摘要: |
| 目的:寻找声带白斑嗓音分析中敏感指标,探讨嗓音分析对于诊断声带白斑的临床意义.方法:使用Dr.Speech软件对63例声带白斑患者(男47例,女16例)进行嗓音分析,计算基频微扰(Jitter)、幅度微扰(Shimmer)、声门噪声能量(NNE)、谐噪比(HNR)及基频值(Fo),并按不同性别与各自正常对照组(均30例)和声带息肉患者(均30例)嗓音分析的各指标进行对比.结果:男性声带白斑患者的Jitter、Shimmer明显高于正常男性对照组和男性声带息肉患者;HNR低于正常男性对照组,高于声带息肉男性组;NNE低于正常男性对照组和男性声带息肉患者(P均＜0.05);Fo与正常男性对照组和男性声带息肉患者间无统计学差异.女性声带白斑患者的嗓音分析结果与男性类似.结论:Jitter、Shimmer、NNE、HNR指标可作为声带白斑嗓音分析的敏感指标,其中Jitter和Shimmer特异性最强,可作为声带白斑的诊断及疗效评价的参考指标. |
| 关键词: 声带、白斑、声音 |
| DOI：10.3724/SP.J.1008.2006.00826 |
| 投稿时间：2005-12-21修订日期：2006-07-15 |
| 基金项目: |
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| The voice assessment of 63 patients with larynx leukoplakia |
| CHEN Zheng-ming,FAN Jing-ping,YANG Yu-mei,ZHOU Shu |
| (第二军医大学长征医院耳鼻咽喉科,上海,200003;解放军第413医院耳鼻咽喉科,舟山,316000) |
| Abstract: |
| Objective：To search for sensitive indicators for the voice assessment of patients with larynx leukoplakia and to analyze the clinical relevance of voice assessment in diagnosis of larynx leukoplakia. Methods： Sixty-three patients with larynx leukoplakia （including 47 males and 16 females） were subjected to voice assessment by Dr. Speech software and the values of Jitter, Shimmer, normalized noise energy （NNE）, harmonics-to-noise ratios （HNR）, and fundamental frequency （Fo） were calculated. The results of the 47 male leukoplakia patients and 16 females were compared with those of normal controls （male 30, female 30） and of patients with vocal cord polyp （male 30, female 30） . Results： The Jitter and Shimmer values of male leukoplakia patients were obviously higher than those of normal controls and patients with vocal cord polyp; their HNR value was lower than those of normal controls and higher than those of patients with vocal cord polyp; their NNE value was lower than those of normal controls and patients with vocal cord polyp （all P〈0.05）; and their Fo value was similar to those of normal controls and patients with vocal cord polyp. Female leukoplakia patients had a similar result to the male ones. Conclusion： The Jitter, Shimmer, NNE, and HNR values can be used as sensitive indicators for voice assessment of patients with larynx leukoplakia; among them the Jitter and Shimmer values have the strongest sensitivity and can be used as indicators for diagnosis and prognosis of larynx leukoplakia. |
| Key words: vocal cords leukoplakia sound |
