| 摘要: |
| 目的：验证Sylvester等提出的非肌层浸润性膀胱癌术后复发和进展危险评分系统用于我国汉族膀胱癌患者预后评估的可行性。方法：根据Sylvester等提出的非肌层浸润性膀胱癌术后复发和进展危险评分系统，对长海医院泌尿外科10年间收治的非肌层浸润性膀胱癌患者进行预后风险评分。计算各评分等级膀胱癌1年、5年的复发率和进展率，并与Sylvester等的研究结果进行比较。结果：共收集长海医院泌尿外科1992年1月到2002年1月10年间187例非肌层浸润性膀胱癌患者的信息。根据患者实际情况计算得0分组、1~4分组、5~9分组、10~17分组患者1年实际复发率分别为13.3%、21.0%、36.0%、 58.8%，5年实际复发率分别为26.5%、44.0%、59.5%、82.4%；0分组、2~6分组、7~13分组、14~23分组患者1年实际进展率分别为0、1.4%、5.1%、15.6%，5年实际进展率分别为1.1%、6.7％、14.8％、53.1％。上述结果与Sylvester等的研究结果比较均无显著差异。结论：在我院研究人群中，Sylvester等所建立的危险评分系统可以用于非肌层浸润性膀胱癌术后复发和进展危险预测。其结果是否适用于我国汉族人群，有待于在更大人群中进一步验证。 |
| 关键词: 膀胱肿瘤 经尿道前列腺切除术 预后 危险性评估 |
| DOI：10.3724/SP.J.1008.2007.01365 |
| 投稿时间：2007-03-16 |
| 基金项目: |
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| Recurrence and progression of nonmuscle invasive urothelial bladder carcinoma after transurethral resection: risk prediction |
| CAI Chen1 , SUN Ying-hao2*, XU Chuan-liang2 |
| (1.Department of Special Diagnosis, Changhai Hospital, Second Military Medical University, Shanghai 200433, China; 2. Department of Urinary Surgery, Changhai Hospital) |
| Abstract: |
| Objective：To assess the feasibility of applying the scoring system proposed by Sylvester RJ in predicting recurrence and progression of nonmuscle invasive bladder carcinoma (NIBC) after transurethral resection (TUR). Methods: Using Sylvester RJ’s predicting system, we evaluated the risk factors for recurrence and progression of NIBC after TUR in patients treated in the Department of Urinary Surgery of Changhai Hospital in a ten-year period. The 1-year, 5-year recurrence rates and progression rates of patients with different scores were calculated and the results were compared with the results of Sylvester RJ system. Results: The data of 187 patients with NIBC treated in the Department of Urinary Surgery of Changhai Hospital from Jan. 1992 to Jan. 2002 were collected. The 1-year recurrence rates in 0 score group, 1-4 score group, 5-9 score group and 14-23 score group were 13.3%, 21.0%, 36.0% and 58.8%, respectively; their 1-year progression rates were 0, 1.4%, 5.1% and 15.6%, respectively. The 5-year recurrence rates were 26.5%, 44.0%, 59.5% and 82.4%, respectively; and their progression rates were 1.1%, 6.7%, 14.8%, and 53.1%, respectively. The above results were not significantly different from those of Sylvester RJ’s (P>0.05).Conclusion: Sylvester RJ’s system can be used for the patients in our hospital for predicting risk factors of recurrence and progression of NIBC after operation. Whether the system is suitable for all Chinese patient still need further study in greater population. |
| Key words: bladder neoplasms transurethral resection of prostate prognosis risk assessment |
