| 摘要: |
| 目的：从文献计量的角度揭示近年来阿尔茨海默病（AD）的国际研究趋势。 方法：利用关键词Alzheimer*对1996-2005年美国科学情报研究所(ISI)的SCI（Science Citation Index）、Medline、ESI(Essential Science Indicators)数据库进行检索，采用Thomson Data Analyzer、SPSS软件对检索到的文献进行统计分析。结果：1996-2005年这10年间国际范围内AD研究科研产出呈现不断上升的趋势，2002-2005年增长速度明显加快。 美国仍然处于本领域领先地位。目前AD研究主要围绕“淀粉蛋白假说”展开，热点是β淀粉纤维、AD的诊断方法，AD与心脑血管之间的联系等。结论：AD研究领域受到的重视将越来越大，相应的科研产出量将持续增加，研究热点仍将围绕β淀粉纤维。 |
| 关键词: 阿尔茨海默病 文献计量学 研究趋势 |
| DOI：10.3724/SP.J.1008.2007.01369 |
| 投稿时间：2007-05-25 |
| 基金项目: |
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| Bibliometric analysis of studies on Alzheimer’s disease from 1996 to 2005 |
| YANG Dan1,2, XIAO Hong1* |
| (1.Shanghai Information Center for Life Sciences, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031，China;2.Graduate School of the Chinese Academy of Sciences, Beijing 100039) |
| Abstract: |
| Objective：To analyze the recent studies worldwide on Alzheimer’s diseases (1996 to 2005) from a bibliometric perspective.Methods: Articles were searched from SCI (Science Citation Index), Medline and ESI (Essential Science Indicators) databases using “Alzheimer*” as the keyword. Thomson Data Analyzer and SPSS software was used for statistical analysis. Results: Alzheimer’s diseases related researches had an increasing tendency during 1996 to 2005, and the increase was obviously accelerated during 2002-2005. The US-led developed countries were in the leading position in the research of Alzheimer’s disease. Currently the research on Alzheimer’s diseases was mainly around the amyloid hypothesis, focusing on beta-amyloid fibrils, Alzheimer’s disease diagnosis, the relationship between Alzheimer disease and cardiovascular diseases, and so on.Conclusion: More studies on Alzheimer’s disease are expected in the future and more articles will be published on the fields; the studies will be largely based on the research of beta-amyloid fibrils. |
| Key words: Alzheimer disease bibliometric analysis research trend |
