| 摘要: |
| 胰腺癌动物模型是胰腺癌实验研究中的重要组成部分，建立理想的胰腺癌动物模型将为研究者们探索胰腺癌发病机制提供有效工具，本文总结了近年来胰腺导管腺癌小鼠模型的建立方法，分析了不同模型的优缺点并作一展望。 |
| 关键词: 胰腺肿瘤 胰腺上皮内瘤变 胰腺导管腺癌 动物 模型 |
| DOI：10.3724/SP.J.1008.2008.00435 |
| 投稿时间：2007-07-23修订日期：2008-03-13 |
| 基金项目: |
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| Mouse model of pancreatic ductal adenocarcinoma:an update |
| WANG Wei,LI Zhao-shen* |
| (Department of Gastroenterology, Changhai Hospital, Second Military Medical University, Shanghai 200433, China) |
| Abstract: |
| Animal models of pancreatic cancer are important for the experiments of pancreatic cancer research.An ideal animal model of pancreatic cancer provides effective tool for exploring the tumorigenesis of pancreatic cancer.This paper summarizes the methods for establishing mouse model of pancreatic ductal adenocarcinoma and discusses interpretd the advantages and disadvantages of different models. |
| Key words: pancreatic neoplasms pancreatic intraepithelial neoplasia pancreatic ductal adenocarcinoma animal model |
