| 摘要: |
| 目的：探索熵聚堆方法在络气虚滞诊断标准研究中的应用.方法：首先根据临床流行病学调查获得400例血管内皮功能障碍的四诊资料,以熵聚堆方法提取血管内皮功能障碍络气虚滞证的中医症状信息;然后计算络气虚滞证中各症状的关联度并确定血管内皮功能障碍络气虚滞证诊断阈值;最后根据临床流行病学诊断性试验研究方法,从灵敏度、特异度、符合率3个方面对此诊断标准进行回顾性和前瞻性检验.结果：建立的血管内皮功能障碍络气虚滞证的诊断标准有较好的诊断效能.结论：熵聚堆方法适用于中医证候诊断标准的研究,方法科学严谨,有临床实用价值.[著者文摘] |
| 关键词: 络气虚滞 熵 证候 诊断标准 |
| DOI：10.3724/SP.J.1008.2007.00778 |
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| 基金项目:国家重点基础研究发展计划（973计划） |
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| Application of entropy partition method for studying diagnostic criteria of Traditional Chinese Medicine syndrome |
| GAO Huai-lin , ZHANG Fu-sheng ,WU Yi-ling ,CHEN Jing, XI Guang-cheng , JIA Zhen-hua , YUAN Guo-qiang , WU Xiang-chun, WEI Cong, GU Chun-hua, CHEN Jian-xin |
| (1. Yiling Hospital, Hebei Medical University, Shijiazhuang 050017, China; 2. Hebei Yiling Pharmaceutical Research Institute, Shijiazhuang 050035; 3. Key Laboratory of Complex Systems and Intelligence Science, Institute of Automation, Chinese Academy of Science, Beijing 100080) |
| Abstract: |
| Objective.. To investigate the application of entropy partition method （EPM） for studying the diagnostic criteria of Traditional Chinese Medicine （TCM） syndrome. Methods.. A clinical epidemiological survey was conducted in 400 patients with vascular endothelial dysfunction and the EPM was adopted to extract the TCM syndrome elements of ＂stagnancy of collateral-Qi in a deficiency condition＂, the correlation degree between each symptom of ＂stagnancy of collateral-Qi in a deficiency condition＂ was calculated and the diagnostic threshold of vascular endothelial dysfunction was established. The sensitivity, specificity and accuracy of the EPM-associated diagnostic criteria were assessed by comparing with those of clinical epidemiology. Results： The diagnostic criteria of ＂stagnancy of collateral-Qi in a deficiency condition＂ in vascular endothelial dysfunction established with EPM had a satisfactory diagnostic efficiency. Conclusion： EPM for complex system is suitable for studying the diagnostic criteria of TCM syndrome. EPM is a scientific and strict method and has great value in clinical practice.[著者文摘] |
| Key words: stagnancy of collateral-Qi in deficiency condition entropy symtom complex diagnostic criteria |
