| 摘要: |
| 最近Ohsawa等报道，呼吸氢气能通过抗氧化作用，减少动物脑和肝缺血再灌注引起的细胞凋亡。实际上，人和动物消化道内许多正常细菌能产生氢气，这些氢气可被消化道吸收进入血液循环。考虑到小鼠部分器官内氢气水平已达到产生抗氧化作用的浓度，我们认为，氢是一种内源性抗氧化物质。 |
| 关键词: 氢 抗氧化剂 再灌注损伤 |
| DOI：10.3724/SP.J.1008.2008.00233 |
| 投稿时间：2008-01-13修订日期：2008-01-28 |
| 基金项目: |
|
| Hydrogen - an endogenous antioxidant in the body |
| SUN Xue-jun1*,John H Zhang2 |
| (1.Department of Diving Medicine, Faculty of Naval Medicine,Second Military Medical University,Shanghai 200433,China;2.Department of Physiology and Pharmacology,Loma Linda University School of Medicine,Loma Linda,California,USA) |
| Abstract: |
| Recently,Ohsawa et al. provide evidence that inhaled hydrogen gas has antioxidant and antiapoptotic activities that protect the brain and liver against ischemia-reperfusion injury. In fact,there is some endogenous hydrogen produced by intestinal bacteria within animal and human.The concentration of hydrogen in some mice tissues reached the antioxidant effect in their paper demonstrates,so we think that hydrogen should be an endogenous antioxidant in the body. |
| Key words: hydrogen antioxidants reperfusion injury |
