| 摘要: |
| 通过综述创伤后应激障碍（PTSD）脑结构影像变化的相关研究及其最新进展，阐明了PTSD患者相关脑区体积、灰质、白质密度的减小，主要表现为海马、胼胝体与前扣带回等区域脑结构影像的变化，其中，PTSD患者胼胝体的变化具有特异性；指出了白质与灰质结构影像分析是目前该研究领域中前沿性和战略性的两个研究方向；同时提出了PTSD与脑结构影像变化的因果关系研究是今后该领域亟待研究解决的课题。 |
| 关键词: 创伤后应激障碍 脑结构影像 脑体积 脑灰质 脑白质 |
| DOI：10.3724/SP.J.1008.2009.0305 |
| 投稿时间：2008-10-29修订日期：2009-02-10 |
| 基金项目:教育部重点课题（DBB010502）. |
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| Imaging changes of brain structure in post-traumatic stress disorders: recent progress |
| WANG Shu-zhen1*, FU Jian-she2, WANG Fang3 |
| (1. Institute of Applied Psychology, School of Public Administration, Northwest University, Xi′an 710127,China;2. Center of Imaging, the Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710004;3. Department of B-ultrasonic,The Peoples’ Hospital of Sanyuan County, Xianyang 713800) |
| Abstract: |
| The brain structural imaging changes in patients with post-traumatic stress disorders (PTSD) and the related research progress are reviewed. It is elucidated that the volume decrease and the density reductions of gray and white matters in PTSD patients are mainly manifested as the imaging changes of the hippocampus, callus, and anterior cingulate cortex (ACC). The imaging change of callus is characteristic in PTSD patients. The image structure analyses of the white matter and gray matter are the current frontiers and strategic trends of PTSD-related research. Meanwhile, it is pointed out that the relationship between PTSD and brain structure imaging is a problem needs to be urgently solved. |
| Key words: post-traumatic stress disorders brain structural imaging brain volume gray-matter white-matter |
