| 摘要: |
| 目的对中药射干Belamcanda chinensis(L.)DC根茎80%乙醇提取物进行化学成分分析。方法利用硅胶色谱、Sephadex LH-20色谱以及反相HPLC等手段进行分离纯化,应用MS、NMR等光谱方法对分得的化合物进行结构鉴定。结果从射干根茎中分离并鉴定了10个化合物,分别为鸢尾苷(tectoridin,Ⅰ),香草乙酮(acetovanillone,Ⅱ),对羟基苯乙酮(4-hydroxy-acetophenone,Ⅲ),β-谷甾醇(β-sitosterol,Ⅳ),β-胡萝卜苷(β-daucosterol,Ⅴ),5,7,4′-三羟基-3′,5′-二甲氧基黄酮(5,7, 4′-trihydroxyl-3′,5′-dimethoxyflavone,Ⅵ),木犀草素(luteolin,Ⅶ),芹菜素(apigenin,Ⅷ),5,7,4′-三羟基二氢黄酮(5,7,4′-trihydroxyflavanones,Ⅸ),异鼠李素(isorhamnetin,Ⅹ)。结论化合物Ⅵ、Ⅶ、Ⅷ、Ⅸ为首次从射干中分离得到。 |
| 关键词: 干 化学成分 黄酮类 |
| DOI：10.3724/SP.J.1008.2010.01120 |
| 投稿时间：2010-03-12修订日期：2010-07-28 |
| 基金项目:上海市科委登山计划 (7dZ19721-2), 上海市重点实验室建设资助(B906). |
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| Studies on chemical constituents of Belamcanda chinensis |
| FENG Chuan-wei, SHEN Gang, Chen hai-sheng |
| (Department of Natural Medicinal Chemistry, School of Pharmacy, Second Military Medical University, Shanghai 200433, China) |
| Abstract: |
| ObjectiveTo investigate the chemical constituents of 80% ETOH extract from rhizome of Belamcanda chinensis (L.) DC. MethodsThe constituents were isolated and purified by chromatography on silica gel, Sephadex LH-20 and HPLC; the structures of the compounds were determined by MS and NMR spectral analysis. ResultsTen constituents were identified from rhizome of Belamcanda chinensis (L.) DC, including tectoridin (Ⅰ), acetovanillone (Ⅱ), 4-hydroxy-acetophenone (Ⅲ), β-sitosterol (Ⅳ), β-daucosterol(Ⅴ), 5,7,4′-trihydroxyl-3′,5′-dimethoxyflavone (Ⅵ), luteolin (Ⅶ), apigenin (Ⅷ), 5,7,4′-trihydroxyflavanones (Ⅸ), and isorhamnetin (Ⅹ).ConclusionCompounds Ⅵ, Ⅶ, Ⅷ, and Ⅸ have been isolated from rhizome of Belamcanda chinensis for the first time. |
| Key words: Belamcanda chinensis chemical constituents flavones |
