| 摘要: |
| 目的 对药用狗牙花(Ervatamia officinalis) 茎叶的化学成分进行分离及结构鉴定。方法 利用硅胶柱、凝胶柱及反相硅胶柱等色谱柱技术进行分离,根据理化性质及波谱学方法进行结构鉴定。结果共分离并鉴定了10个化合物:α-香树醇(α-amyrin,1)、α-香树酯醇乙酸酯(α-amyrin acetate,2)、棕榈酸(palmitic acid,3)、正三十四烷醇(tetratriacontanol,4)、豆甾醇(stigmasterol,5)、β-胡萝卜苷(β-daucosterol,6)、羽扇豆醇(lupeol,7)、毛蕊异黄酮(calycosin,8)、木犀草素(luteolin,9)、蓝萼甲素(glaucocalyxin A,10)。结论 化合物1、3~10为首次从该植物中分离得到,化合物7、9、10为首次从该属植物中分离得到。 |
| 关键词: 药用狗牙花 狗牙花属 化学成分 结构鉴定 |
| DOI：10.3724/SP.J.1008.2011.0996 |
| 投稿时间：2011-06-14修订日期：2011-07-12 |
| 基金项目:国家自然科学基金(20872178). |
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| Chemical constituent analysis in leaf and stem of Ervatamia officinalis |
| ZHU Zhi-xiang1,ZHAO Ji-hua2,CHEN Hai-sheng1* |
(1. Department of Natural Medicinal Chemistry, School of Pharmacy, Second Military Medical University, Shanghai 200433, China
2. Hospital of No. 71887 Troop, PLA Jinan Military Area Command, Changdao 265800, Shandong, China
*Corresponding author.) |
| Abstract: |
| ObjectiveTo extract and identify the chemical constituents in the leaf and stem of Ervatamia officinalis. MethodsThe solvent extraction approach and silica column chromatography were used to separate the chemical constituents, and their structures were identified by physicochemical properties and spectra analysis. ResultsTen compounds were isolated and their structures were identified as α-amyrin(1),α-amyrin acetate(2),palmitic acid(3),tetratriacontanol(4),stigmasterol(5),β-daucosterol(6), lupeol(7), calycosin(8), luteolin(9), and glaucocalyxin A(10). ConclusionCompound 1,3~10 have been isolated from this plant for the first time,and compound 7, 9 and 10 have been isolated from Ervatamia genus for the first time. |
| Key words: Ervatamia officinalis Ervatamia genus chemical constituents structure identification |
