| 摘要: |
| N-亚硝基化合物是环境以及食物中广泛存在的一类化学物质,迄今已发现300多种，这类化合物对动物的致癌性已经得到广泛的实验证实,至今尚未发现一种动物对这类化合物具有抵抗力[1]。 |
| 关键词: 食管肿瘤 N-甲基-N-戊基亚硝胺 有机合成 |
| DOI：10.3724/SP.J.1008.2012.00692 |
| 投稿时间：2012-02-20修订日期：2012-05-20 |
| 基金项目: |
|
| Synthesis of N-methyl-N-amylnitrosamine for establishing esophageal cancer model |
| WANG Feng-chun1,WU Ai-qun2,MIAO Zhen-yuan3* |
(1. Department of Medical Service, General Hospital, PLA Beijing Military Area Command, Beijing 100700, China
2. Department of Anatomy, College of Basic Medical Sciences, Second Military Medical University, Shanghai 200433, China
3. Department of Medicinal Chemistry, School of Pharmacy, Second Military Medical University, Shanghai 200433, China
*Corresponding author.) |
| Abstract: |
|
| Key words: esophageal neoplasms N-methyl-N-amylnitrosamine organic synthesis |
