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急性心肌梗死患者行经皮冠状动脉介入术后住院期间死亡的危险因素分析
崔海明,桂艳萍,任雨笙*,杨靖,梁春,潘晓明,樊民,顾兴建,吴宗贵
0
(第二军医大学长征医院心血管内科,上海 200003
*通信作者)
摘要:
目的探讨影响急性心肌梗死(AMI)患者行经皮冠状动脉介入术(PCI)后住院期间死亡的危险因素。方法回顾性分析2009年1月至2011年9月因AMI入住我院并行PCI的275例患者的一般情况、既往史、入院情况、术中及术后情况、并发症等资料,对可能影响术后死亡的危险因素通过logistic回归模型进行分析。结果多因素logistic回归分析表明,女性(P=0.047,OR=2.91)、广泛前壁心肌梗死(P=0.044,OR=3.07)、肾功能不全史(P=0.021,OR=7.98)、发生心源性休克(P=0.008,OR=15.71)、术后心肌梗死溶栓(TIMI)血流<3级(P=0.016,OR=5.61)、置入主动脉内球囊反搏(IABP;P=0.043,OR=3.49)。结论影响AMI患者行PCI术后院内死亡的危险因素为女性、广泛前壁心肌梗死、置入IABP、术后TIMI血流<3级、肾功能不全史和发生心源性休克。
关键词:  心肌梗死  经皮冠脉成形术  住院死亡  危险因素  logistic模型
DOI:10.3724/SP.J.1008.2012.00868
投稿时间:2012-04-11修订日期:2012-07-10
基金项目:
Risk factors analysis of in-hospital death of acute myocardial infarction patients following percutaneous coronary intervention
CUI Hai-ming,GUI Yan-ping,REN Yu-sheng*,YANG Jing,LIANG Chun,PAN Xiao-ming,FAN Min,GU Xing-jian,WU Zong-gui
(Department of Cardiovasology, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China
*Corresponding author.)
Abstract:
ObjectiveTo explore the risk factors of in-hospital death of acute myocardial infarction (AMI) patients following percutaneous cornary intervenion (PCI). MethodsWe retrospectively analyzed the clinical data of 275 AMI patients, including the general condition, medical history, admission, intra- and post-operation condition, and complication. The patients underwent PCI in our hospital from January 2009 to September 2011. Logistic regression analysis was used to predict the risk factor of in-hospital death of AMI patients following PCI. ResultsLogistic regression analysis found that female sex (P=0.047, OR=2.91), extensive anterior myocardial infarction (P=0.044, OR=3.07), history of renal insufficiency (P=0.021, OR=7.98), cardiogenic shock (P=0.008, OR=15.71), postoperative thrombolysis in myocardial infarction (TIMI) flow grade <3 (P=0.016, OR=5.61), and placement of the intra-aortic balloon pump(IABP, P=0.043,OR=3.49) were associated with an increased risk of in-hospital mortality of AMI patients following PCI. ConclusionFemale sex, extensive anterior myocardial infarction, placement of the IABP, postoperative TIMI flow grade <3, history of renal insufficiency, and cardiogenic shock are the risk factors of in-hospital death of AMI patients following PCI.
Key words:  Acute Myocardial Infarction  Percutaneous Cornary Intervenion  in-hospital mortality  prediction  Logistic Regression Analysis