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输尿管支架置入联合放疗治疗宫颈癌合并输尿管梗阻
梁燕1,3△,傅志超2△,陈于1*,朱凌锋2,林贵山2,李东石2,吴建勇2
0
(1.第二军医大学长海医院妇产科, 上海 200433
2.南京军区福州总医院放疗科,福州 350025
*共同第一作者
*通信作者)
摘要:
目的 探讨输尿管支架置入联合放疗宫颈癌合并输尿管梗阻的临床疗效。方法 回顾 性分析63例妇科颈癌合并输尿管梗阻患者放疗前给予膀胱镜下输尿管逆行插管留置后给予根治性同步放化疗,了解输尿管支架置入成功率及肾功能改善情况,并观察置入输尿管支架对放疗疗效的影响。结果 50例患者支架置入成功,输尿管梗阻患者肾积水程度较置管前比较明显好转,肾功能明显改善,患者近期疗效佳,完全缓解35例,部分缓解12例,疾病稳定3例,总有效率为94%,双J管对放疗无明显影响。结论 输尿管支架置入联合放疗是宫颈癌合并输尿管梗阻的有效临床手段,未有明显毒副反应,值得推广应用。
关键词:  宫颈肿瘤  输尿管梗阻  支架  放射疗法
DOI:
投稿时间:2013-07-05修订日期:2013-09-30
基金项目:
Radiotherapy combined with retrograde ureteral catheterization in treatment of cervical cancer complicated with ureteral obstruction
LIANG Yan1,3△,FU Zhi-chao2△,CHEN Yu1*,ZHU Ling-feng2,LIN Gui-shan2,LI Dong-shi2,WU Jian-yong2
(1. Department of Obstetrics and Gynecology, Changhai Hospital, Second Military Medical University, Shanghai 200433, China
2. Department of Radiotherapy,Fuzhou General Hospital, PLA Nanjing Military Area Command, Fuzhou 350025, Fujian, China
*Corresponding author.)
Abstract:
To explore therapeutic value of radiotherapy combined retrograde ureteral catheterization on Cervical cancer complicated with ureteral obstruction. Methods 63 cases of cervical cancer patients complicated with ureteral obstruction were retrospectively analyzed With ureteral stent guided by cystoscope,retrograde double J stent was performed before Concurrent chemoradiotherapy. Ureteral stents success rate and renal function were compared before and after cannulation. The effect of ureteral stent placement on radiotherapy in Cervical cancer complicated with ureteral obstruction was observed. Results 50 of 63 patients were Successful in retrograde ureteral catheterization. Renal function significantly improved compared with the pre-operation. The overall response rate was 94% (47/50),including CR,35 cases;PR,l 2 cases;NC,3 cases.Double J tube had no significant effect on radiation therapy. Conclusions Radiotherapy combined retrograde ureteral catheterization is an effective method to treat cervical cancer complicated with ureteral obstruction. The technique is easy and safe without complications.
Key words:  uterine cervical neoplasms  ureteral obstruction  stents  radiotherapy