| 摘要: |
| 目的 应用超声射频技术评价2型糖尿病患者左右颈动脉硬化程度差异及相关因素。方法 应用超声射频技术获取受检者左、右侧颈动脉顺应系数(compliance coefficient, CC)和脉搏波速度(pulse wave velocity, PWV)。计算左、右侧参数值之比, 获取CCratio和PWVratio参数。参数在组内采用左右侧比较, 在组间采用同侧比较。分析CCratio和PWVratio的相关因素。结果 2型糖尿病患者左侧颈动脉PWV高于右侧, 且CC低于右侧(P<0.05)。对照组CC和PWV在左右侧差异无统计学意义;与对照组相比, 2型糖尿病患者左侧PWV增高, 右侧颈动脉CC增高(P<0.05)。PWVratio和CCratio在两组间差异有统计学意义(P<0.05)。多元线性回归分析提示, 年龄、病程、三酰甘油(TG)和收缩压是PWVratio增高的独立危险因素。年龄和高密度脂蛋白胆固醇(HDL-C)是CCratio的独立危险因素。结论 2型糖尿病患者左右颈动脉硬化程度不同, 存在差异性。年龄、病程、血压、TG和HDL-C是这种差异性的独立因素。 |
| 关键词: 糖尿病血管病变 内中膜厚度 顺应性 脉搏波速度 |
| DOI：10.3724/SP.J.1008.2014.01333 |
| 投稿时间：2014-04-16修订日期：2014-07-26 |
| 基金项目:上海市卫生和计划生育委员会基金(201440290). |
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| Ultrasound radio-frequency in evaluating atherosclerosis degrees of bilateral common carotid arteries in patients with type 2 diabetes |
| LI Zhao-jun1△,LUO Xiang-hong2△,DU Lian-fang1*,SU Yi-jin1,2,SHAO Chun-juan1,2 |
(1. Department of Ultrasound, the First People's Hospital of Shanghai, Shanghai Jiaotong University, Shanghai 200080, China;
2. Department of Echocardiography, the First People's Hospital of Shanghai, Shanghai Jiaotong University, Shanghai 200080, China
△Co-first authors.
*Corresponding author) |
| Abstract: |
| Objective To use ultrasound radio-frequency (RF) technology for investigating atherosclerosis degree difference between the left and right common carotid arteries (CCA) in patients with type 2 diabetes, and to analyze the related factors. Methods The compliance coefficient (CC) and pulse wave velocity (PWV) of the left and right common carotid arteries (CCA) were obtained by ultrasound RF technology. The ratios of the left to right CCAs were calculated: CCratio and PWVratio. The difference within groups was observed by left and right comparison and that between groups was observed by comparison of the same side. The relevant factors of CCratio and PWVratio were analyzed. Results (1) PWV of the left CCA was significantly higher than that of the right one and CC was significantly lower than that of the right one in patients with type 2 diabetes (P<0.05). The CC and PWV were not significantly different between the left and right CCAs in the control group. (2) Compared with the control group, patients with type 2 diabetes had significantly increased left PWV and right CC (P<0.05). (3) PWVratio and CCratio were significantly different between the two groups (P<0.05). Multiple linear regression analysis showed that age, disease course, triglycerides and systolic blood pressure (SBP) were the independent risk factors for PWVratio; and age, HDL-C were the independent risk factor for CCratio. Conclusion The atherosclerosis degrees are different between the left and right CCA in patients with type 2 diabetes. The age, disease course, SBP, triglyceride and HDL-C are independent risk factors for the differences. |
| Key words: diabetic angiopathies intima-media thickness compliance pulse wave velocity |
