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饮食营养与炎症-癌症危险性的关系
倪翀1,郭世昌2,杜琰1,曹广文1*
0
(1. 第二军医大学热带医学与公共卫生学系流行病学教研室, 上海 200433;
2. 第二军医大学学员旅学员5队, 上海 200433
*通信作者)
摘要:
慢性炎症在癌症的进化发育中起促进作用。某些饮食种类及生活习惯等可干预因素对炎-癌转化有重要影响。日常饮食中的各类食物可按照一定的标准分为促炎症食物和抗炎症食物,通过促进或抑制体内的炎症微环境影响某些癌症的发生和发展。由不良饮食和体力活动缺乏导致的肥胖本身即可营造炎症环境,与营养因素共同推动癌症的进化发育进程。通过对饮食结构的调节和生活习惯的改变可控制炎-癌转化过程,对癌症病因预防具有重要价值。
关键词:  肿瘤  炎症  饮食习惯  肥胖
DOI:10.3724/SP.J.1008.2015.01117
投稿时间:2015-02-26修订日期:2015-04-16
基金项目:国家重点基础研究发展计划("973"计划)(2015CB554000).
Role of diet and nutrition in the risk of inflammation-to-cancer
NI Chong1,GUO Shi-chang2,DU Yan1,CAO Guang-wen1*
(1. Department of Epidemiology, Faculty of Tropical Medicine and Public Health, Second Military Medical University, Shanghai 200433, China;
2. The 5th Team of Student Brigade, Second Military Medical University, Shanghai 200433, China
*Corresponding author.)
Abstract:
Chronic inflammation plays an important role in cancer evolution and development. Some adjustable factors concerning diet and lifestyles can influence the transition from chronic inflammation to cancer. According to an established standard, food can be classified into pro-inflammatory food and anti-inflammatory food, which may affect the occurrence and progression of some cancers via promoting or inhibiting inflammatory microenvironment. Obesity caused by unhealthy diet and lack of physical activities can create inflammatory microenvironment, together with nutritional factors, they can promote cancer evolution and development. It is of great significance to improve food structure and lifestyle to control the evolution and development of inflammation-associated cancers.
Key words:  neoplasms  inflammation  food habits  obesity