| 摘要: |
| 目的 探讨30岁以下肾肿瘤患者的发病情况、临床病理特征及治疗预后特点。 方法 回顾性分析2001年1月至2014年12月长海医院收治的所有30岁以下肾肿瘤患者的临床资料,对患者的基本信息、临床症状、手术情况、病理结果和预后情况进行总结分析。 结果 本组患者共有137例,占同期所有肾肿瘤患者的3.84%(137/3570)。男性67例(48.9%),女性70例(51.1%),平均年龄为(24.47±4.80)岁。因体检发现79例(57.66%),腹部或腰部疼痛起病39例(28.47%),单纯肉眼血尿10例,因包块发现者7例,另有2例因尿频尿急就诊。137例患者中,手术治疗133例(占97.1%),其余4例为内科保守治疗。获术后病理125例,其中肾细胞癌75例(占60%),血管平滑肌脂肪瘤42例(33.6%),肾母细胞瘤6例,神经内分泌肿瘤、肾小球旁细胞瘤各1例。121例获访病例中,肾细胞癌64例,3年生存率为82.86%,5年生存率为61.53%；所有血管平滑肌脂肪瘤患者预后均良好,无一例死亡。6例肾母细胞瘤患者中,2例死于肿瘤转移。1例神经内分泌瘤及1例肾小球旁细胞瘤患者预后良好。结论 30岁以下肾肿瘤患者中仍然以恶性为主,但良性血管平滑肌脂肪瘤占相当比例。定期体检利于肿瘤的早期发现、改善预后。 |
| 关键词: 肾肿瘤 肾细胞癌 肾血管平滑肌脂肪瘤 青年人 预后 |
| DOI：10.16781/j.0258-879x.2016.07.0920 |
| 投稿时间：2015-12-06修订日期：2016-04-28 |
| 基金项目:国家自然科学基金（81272817，81572521），上海市“领军人才”计划（2013046），上海市科技人才计划（13XD1400100）. |
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| Renal tumor in patients aged 30 years and below: an analysis of clinical characteristics |
| SHI Jia-zi1△,WANG Zhi-xiang1,2△,WANG Jie1,LIU Bing1,YANG Qing3,YE Hua-mao3,WANG Lin-hui1* |
(1. Department of Urology, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China;
2. Department of Urology, No. 458 Hospital of PLA, Guangzhou 510000, Guangdong, China;
3. Department of Urology, Changhai Hospital, Second Military Medical University, Shanghai 200433, China
* Corresponding author) |
| Abstract: |
| Objective To evaluate the incidence, clinicopathologic features, treatments and prognosis of renal tumor patients under the age of 30 years old. Methods The clinical data of renal tumor patients under 30, who were treated between January 2001 and December 2014, were retrospectively analyzed. The general information, incidence, clinical manifestations, pathological outcomes, treatment strategies, and prognosis were analyzed. Results A total of 137 patients were included in this study, which accounted for 3.84% (137/3570) of all renal tumor cases in our hospital at the same period. The mean age of 137 patients was (24.47±4.80) years old, including 67 males and 70 females. 79 patients (57.66%) were diagnosed during health check-up, 39 patients were diagnosed for abdomen or flank pain, gross hematuria and mass as the main clinical symptoms were separately found in 10 and 7 patients, the other 2 patients saw a doctor for urinary frequency and urgency. 133 patients received operations, the rest received conservative medical management. 125 cases of postoperative pathology were got: 75 renal cell carcinomas, 42 angiomyolipomas, 6 nephroblastomas, one neuroendocrine tumor, and one juxtaglomerular cell tumor. 121 patients had been followed-up. The 3 and 5 years survival rates of renal cell carcinoma were 82.86%(29/35)and 61.53%(8/13). 2 cases of nephroblastoma died of tumor metastasis. All the angiomyolipoma, neuroendocrine tumor, juxtaglomerular cell tumor patients had good prognosis. Conclusion Most of renal tumors in patients under the age of 30 years old are malignant. But it is noteworthy that benign angiomyolipoma also accounts for a considerable proportion. Regular health check-up is benefit for early diagnosis and better prognosis. |
| Key words: kidney neoplasms renal cell carcinoma renal angiomyolipoma youth prognosis |
