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胰腺外分泌功能检测方法应用现状
林金欢,胡良皞,廖专,李兆申*
0
(第二军医大学长海医院消化内科, 上海 200433
*通信作者)
摘要:
胰腺外分泌功能的检测主要分为直接检测法和间接检测法,直接检测法主要包括胰泌素试验、胰泌素-雨蛙素试验、内镜下胰腺功能检测、胰泌素刺激下的磁共振胰管成像技术、Lundh试验等,间接检测法主要包括常规血清学检测、粪便脂肪检测、粪便中酶的检测、呼气试验、尿液中特定物质检测等。直接检测法具有较高的准确性,但检测方法有创、相对烦琐;间接检测法虽然无创,但准确性相对较低。本文就胰腺外分泌功能检测方法在临床上的应用现状与进展作一综述。
关键词:  胰腺  胰腺外分泌功能不全  胰泌素试验  呼气试验
DOI:10.16781/j.0258-879x.2017.10.1298
投稿时间:2017-03-15修订日期:2017-05-10
基金项目:国家自然科学基金(81100316,81270541,81470884,81422010,81300355,81470883),上海市晨光计划(12CG40),上海市青年科技启明星计划(13QA1404600).
Clinical application of pancreatic exocrine function examination
LIN Jin-huan,HU Liang-hao,LIAO Zhuan,LI Zhao-shen*
(Department of Gastroenterology, Changhai Hospital, Second Military Medical University, Shanghai 200433, China
*Corresponding author)
Abstract:
Pancreatic exocrine function examination is mainly divided into direct examination and indirect examination methods. Direct examination methods include secretin test, secretin-caerulein test, endoscopic pancreatic function test, secretin-stimulated magnetic resonance pancreatography, Lundh test, etc. Indirect examination methods are comprised of routine serological testing, fecal fat detection, fecal enzyme detection, breath test, urine analysis of specific substances and so on. Direct examination has higher accuracy than indirect examination, but it is more invasive and cumbersome than noninvasive indirect examination. In this review, we summarized the clinical application and progress of pancreatic exocrine function examination.
Key words:  pancreas  exocrine pancreatic insufficiency  secretin test  breath test