| 摘要: |
| 动脉自旋标记（ASL）磁共振灌注成像技术是一种以动脉血中水的氢质子作为内源性对比剂的磁共振灌注成像技术，其以无创、简便、成本低、可定量测量脑血流量（CBF）、可重复性高等优点得到了临床的广泛关注和应用。如今，颅脑疾病是国内外临床及科研工作者最为关注的高发疾病之一，而ASL磁共振灌注成像技术对颅脑疾病的检查和诊断大有裨益。本文综述了近几年来有关ASL磁共振灌注成像技术在评估脑血管疾病、脑肿瘤及精神疾病中应用的国内外文献，为ASL磁共振灌注成像技术在颅脑疾病中的后续研究提供帮助。 |
| 关键词: 自旋标记物 磁共振成像 脑血管障碍 脑肿瘤 精神障碍 |
| DOI：10.16781/j.0258-879x.2016.12.1512 |
| 投稿时间：2016-07-05修订日期：2016-09-26 |
| 基金项目:国家自然科学基金（81270413）. |
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| Application of perfusion magnetic resonance imaging with arterial spin labeling in craniocerebral diseases |
| SHI Zhang,LIU Qi* |
(Department of Radiology, Changhai Hospital, Second Military Medical University, Shanghai 200433, China
* Corresponding author) |
| Abstract: |
| Arterial spin labeling (ASL) in perfusion magnetic resonance imaging is based on endogenous contrast (hydrogen proton in arterial blood), and it has drawn widespread clinical attention and application due to its advantages, including noninvasiveness, convenient operation, low cost, quantitative measurement of cerebral blood flow(CBF), and good repeatability. Recently, the craniocerebral disease has become one of the diseases with highest incidence, which has drawn great attention from scientists and clinicians in and outside China; ASL could be helpful in the clinical examination and diagnosis of craniocerebral diseases. This review summarized recent reports on the clinical application of ASL in the cerebrovascular diseases, brain tumors and mental diseases, so as to provide references for future ASL research in craniocerebral diseases. |
| Key words: spin labels magnetic resonance imaging cerebrovascular disorders brain neoplasms mental disorders |
