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单侧特发性后半规管良性阵发性位置性眩晕的病例特征分析
陈钢钢1,樊辉如1,2,高伟1,张春明1,郑智英1,皇甫辉1,于文永1,温树信1,张芩娜1,杨向茹1,张海利1,王建明1,王娜2,王斌全1*
0
(1. 山西医科大学第一医院耳鼻咽喉-头颈外科, 耳鼻咽喉头颈肿瘤山西省重点实验室, 山西医科大学耳鼻咽喉研究所, 太原 030001;
2. 山西医科大学临床技能教学模拟医院, 太原 030001
*通信作者)
摘要:
目的 分析单侧特发性后半规管良性阵发性位置性眩晕患者的病例特征。方法 总结分析2013年11月至2015年2月在山西医科大学第一医院诊治的214例单侧特发性后半规管良性阵发性位置性眩晕患者的病例特点。结果 单侧特发性后半规管良性阵发性位置性眩晕患者Dix-Hallpike试验时的眼震平均潜伏期为(2.02±1.19)s,平均持续时间为(21.3±14.5)s,其眼震平均潜伏期、平均持续时间均无性别、年龄差异。184例(86.0%)患者1~2次Dix-Hallpike试验即可诱发出典型眼震。162例(75.7%)患者在醒后起床时或夜间睡眠翻身时首次发病。51例(23.8%)患者出现反转相眼震。患者痊愈率为88.3%(189/214),有效率为98.1%(210/214)。14例(6.5%)患者复位后出现耳石转管现象,67例(31.9%)患者复位后残留头晕或走路不稳症状。210例治疗有效的患者中,1、3、6、12、18个月电话随访时复发率分别为0(0/210,0例失访)、5.7%(12/210,0例失访)、8.7%(18/208,2例失访)、11.8%(23/195,15例失访)、17.4%(31/178,32例失访)。结论 单侧特发性后半规管良性阵发性位置性眩晕患者首次发病的高发时段为醒后起床时或夜间睡眠翻身时。大部分患者经过Epley法复位治疗后可痊愈,但长期疗效仍需继续随访观察。
关键词:  良性阵发性位置性眩晕  眼震  耳石转管  残留头晕
DOI:10.16781/j.0258-879x.2017.11.1379
投稿时间:2017-06-15修订日期:2017-09-28
基金项目:
Clinical characteristics of unilateral idiopathic posterior canal-benign paroxysmal positional vertigo
CHEN Gang-gang1,FAN Hui-ru1,2,GAO Wei1,ZHANG Chun-ming1,ZHENG Zhi-ying1,HUANGFU Hui1,YU Wen-yong1,WEN Shu-xin1,ZHANG Qin-na1,YANG Xiang-ru1,ZHANG Hai-li1,WANG Jian-ming1,WANG Na2,WANG Bin-quan1*
(1. Department of Otolaryngology, Head & Neck Surgery, the First Hospital of Shanxi Medical University, Shanxi Key Laboratory of Otorhinolaryngology Head and Neck Cancer, Key Institute and Laboratory of Otolaryngology affiliated to Shanxi Medical University, Taiyuan 030001, Shanxi, China;
2. Simulation Hospital of Clinical Skill Teaching, Shanxi Medical University, Taiyuan 030001, Shanxi, China
*Corresponding author)
Abstract:
Objective To analyze the clinical characteristics of patients with unilateral idiopathic posterior canal-benign paroxysmal positional vertigo (PC-BPPV). Methods We retrospectively analyzed and summarized the clinical characteristics of 214 patients with unilateral idiopathic PC-BPPV who were diagnosed in the First Hospital of Shanxi Medical University from Nov. 2013 to Feb. 2015. Results In the Dix-Hallpike displacement test (D-H test), the average latency of nystagmus in patients with unilateral idiopathic PC-BPPV was (2.02±1.19) s, and the average duration was (21.3±14.5) s. There were no gender or age differences in the latency or duration of nystagmus. Typical nystagmus was induced in 184 cases (86.0%) by one or two D-H tests. The first onset time of 162 cases (75.7%) was in wake up or sleep-tuning at night. Fifty-one cases (23.8%) displayed the reversal phase of nystagmus. The cure rate of patients was 88.3%, and the effective rate was 98.1%. Among 210 patients sensitive to treatment, the recurrence rates were 0 (0/210, 0 case lost to follow-up), 5.7% (12/210, 0), 8.7% (18/208, 2), 11.8% (23/195, 15) and 17.4% (31/178, 32) on 1st, 3rd, 6th, 12th and 18th month, respectively. Forteen cases (6.5%) had canal switch phenomenon after reduction, and 67 cases (31.9%) had residual dizziness or unstable symptoms after reduction. Conclusion The most common first onset time of patients with unilateral idiopathic PC-BPPV is in wake up or sleep-tuning at night. Most patients can be cured by Epley method, but the long-term efficacy still need follow-up observation.
Key words:  benign paroxysmal positional vertigo  nystagmus  canal switch  residual dizziness