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军事人员对抗睡眠剥夺策略的研究进展
侯成,卢光照,鲁莹,董腾腾,邹豪*
0
(海军军医大学(第二军医大学)药学院药剂学教研室, 上海 200433
*通信作者)
摘要:
现代军事斗争和非军事行动呈现出强度大、突发状况多、连续工作时间长的特点,这势必会造成军事人员的睡眠剥夺。然而高强度的作业需要军事人员随时保持良好的工作能力,突发紧急状况需要军事人员保持良好的警觉状态,长时间的工作更需要军事人员保持良好的精神状态和认知能力。军事人员如何有效地对抗睡眠剥夺,保持警醒状态和极高的应激能力成为现代军事医学研究的热点与重点。本文就中枢兴奋药物、预防性睡眠药物、预防性睡眠后快速复醒药物及非药物方式等对抗睡眠剥夺的研究进展作一综述。
关键词:  军事人员  睡眠剥夺  中枢兴奋药  镇静催眠药  睡眠诱导  快速复醒  氟马西尼
DOI:10.16781/j.0258-879x.2020.09.1012
投稿时间:2019-10-17修订日期:2020-05-19
基金项目:国家自然科学基金(30801441,81773278),军队后勤科研重大项目(AWS14J011),国家科技部重大新药创制专项(2018ZX09J18110-004).
Strategies against sleep deprivation in military personnel: recent progress
HOU Cheng,LU Guang-zhao,LU Ying,DONG Teng-teng,ZOU Hao*
(Department of Pharmaceutics, School of Pharmacy, Naval Medical University(Second Military Medical University), Shanghai 200433, China
*Corresponding author)
Abstract:
Modern military actions and non-military operations characterized by high-intensity, sudden emergencies and long continuous working inevitably lead to sleep deprivation of military personnel. High-intensity actions require military personnel to maintain excellent action abilities all the times; sudden emergencies need them to maintain alert; and the continuous work need them to maintain a healthy mental state. Therefore, how to effectively combat sleep deprivation, keep alert and have high stress ability have become the focus of modern military medical research. This article reviews the research progress of central nervous system stimulants, preventive sleep medications, sleep induction and rapid recovery drugs, and non-drug measures to combat sleep deprivation.
Key words:  military personnel  sleep deprivation  central nervous system stimulants  sedative hypnotics  sleep induction  rapid recovery  flumazenil