| 摘要: |
| 目前正在暴发流行的新型冠状病毒肺炎（COVID-19）的病原体是严重急性呼吸综合征冠状病毒2（SARS-CoV-2），这是近年来继严重急性呼吸综合征冠状病毒（SARS-CoV）和中东呼吸综合征冠状病毒（MERSCoV）之后发现的能够感染人的第7种冠状病毒。SARS-CoV-2系单股正链RNA病毒，传染性强，人群普遍对其缺乏免疫力，疫情目前仍在持续。2020年1月30日（当地时间），WHO将此次疫情列为国际关注的突发公共卫生事件（PHEIC）。本文就SARS-CoV-2病原学、致病性及COVID-19的检测诊断、预防控制和临床治疗等领域的进展进行讨论。 |
| 关键词: 严重急性呼吸综合征冠状病毒2 新型冠状病毒肺炎 病原学 诊断 预防 治疗 |
| DOI：10.16781/j.0258-879x.2020.02.0117 |
| 投稿时间：2020-02-07修订日期：2020-02-13 |
| 基金项目:国家传染病重大专项课题（2017ZX10304403-003）. |
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| Severe acute respiratory syndrome coronavirus 2 and coronavirus disease 2019 |
| QI Zhong-tian* |
(Department of Biomedical Defense, PLA Key Laboratory of Biodetection and Biodefense, Shanghai Key Laboratory of Medical Biodefense, Faculty of Naval Medicine, Naval Medical University(Second Military Medical University), Shanghai 200433, China
*Corresponding author) |
| Abstract: |
| The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been confirmed as the etiological pathogen of the coronavirus disease 2019 (COVID-19). SARS-CoV-2 is the seventh member of coronavirus family that can infect humans after the emergence of the severe acute respiratory syndrome coronavirus (SARS-CoV) and the Middle East respiratory syndrome coronavirus (MERS-CoV). SARS-CoV-2 is a single-stranded, positive-sense RNA virus. Due to its strong infectiousness and the lack of immunity in humans, the epidemic of the COVID-19 is still spreading. On January 30, 2020 (local time), the World Health Organization (WHO) defined the epidemics of SARS-CoV-2-infected pneumonia as a Public Health Emergency of International Concern (PHEIC). This paper reviews the etiology and pathogenicity of SARS-CoV-2, and the detection and diagnosis, prevention and control, as well as the treatment of COVID-19. |
| Key words: severe acute respiratory syndrome coronavirus 2 coronavirus disease 2019 etiology diagnosis prevention treatment |
