| 摘要: |
| 细胞焦亡是一种程序性细胞死亡方式，可导致细胞内容物与炎性因子的释放，参与许多疾病的发生发展过程，是目前学术界研究的又一热点。本文旨在阐述细胞焦亡与2型糖尿病、肥胖、非酒精性脂肪性肝病、痛风等代谢性疾病关系的研究进展，进一步拓宽对该类疾病发病机制的认识，为疾病的治疗提供新的思路。 |
| 关键词: 细胞焦亡 2型糖尿病 肥胖 非酒精性脂肪性肝病 痛风 |
| DOI：10.16781/j.0258-879x.2020.11.1250 |
| 投稿时间：2020-02-22修订日期：2020-04-29 |
| 基金项目:国家自然科学基金（81803873）. |
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| Pyroptosis in metabolic diseases: recent progress |
| SHI Jian-xia,LIU Qi,PENG Yong-de* |
(Department of Endocrinology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai 200080, China
*Corresponding author) |
| Abstract: |
| Pyroptosis is a kind of programmed cell death that can lead to the release of cellular contents and inflammatory factors involved in the development of many diseases, and it has become another research focus. This paper is to study the research progress in the relationship between pyroptosis and metabolic diseases, such as type 2 diabetes, obesity, non-alcoholic fatty liver disease and gout, so as to further broaden the understanding of the pathogenesis of these diseases and to provide new treatment strategies. |
| Key words: proptosis type 2 diabetic mellitus obesity non-alcoholic fatty liver disease gout |
