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舰艇官兵肾结石和肾结晶流行病学调查
汤晓静1,2,刘子毓1,徐瑾2,3,吴达熙2,4,李婷2,5,毛志国1*
0
(1. 海军军医大学(第二军医大学)第二附属医院肾脏病科, 上海 200003;
2. 海军军医大学(第二军医大学)第二附属医院驻第 91091部队医务中心内科, 三亚 572000;
3. 海军军医大学(第二军医大学)第二附属医院神经内科, 上海 200003;
4. 海军军医大学(第二军医大学)第二附属医院超声科, 上海 200003;
5. 海军军医大学(第二军医大学)第二附属医院风湿免疫科, 上海 200003
*通信作者)
摘要:
目的 分析舰艇官兵肾结石和肾结晶流行病学特点及其危险因素。方法 收集2021年某舰艇部队官兵体检报告原始数据,包括一般信息、内外科体检结果、超声检查结果、血尿检验结果等,并对官兵进行作训环境及生活习惯调查,分析官兵肾结石/结晶患病情况及影响因素。结果 1 315名官兵中,肾结石/结晶总患病率为6.92%(91/1 315)。肾结石/结晶患病率均随着年龄、军龄和上舰龄的增长而呈增高趋势(P均<0.01)。肾结石/结晶组合并超重者占32.97%(30/91),高于无肾结石/结晶组[17.04%(204/1 197),P<0.01]。肾结石/结晶组饮水量>2 000 mL/d的比例及饮用牛奶的比例均低于无肾结石/结晶组[20.45%(18/88) vs 30.24%(362/1 197),82.95%(73/88) vs 90.64%(1 085/1 197),P均<0.05)]。两组作训环境、水源、饮料摄入、血尿酸水平、尿渗透压差异均无统计学意义(P均>0.05)。多因素logistic回归分析显示,年龄增加和超重是舰艇官兵肾结石/结晶患病的独立危险因素,而多饮水和饮用牛奶是保护性因素(P均<0.05)。结论 舰艇官兵肾结石/结晶患病率较高,其发生与年龄增加、超重、少饮水和不饮牛奶等因素相关。
关键词:  肾石病  流行病学  患病率  影响因素  舰艇官兵
DOI:10.16781/j.CN31-2187/R.20220067
投稿时间:2022-01-17修订日期:2022-09-02
基金项目:军委后勤保障部卫生局应用基础研究项目(21BJZ04),海军军医大学(第二军医大学)第二附属医院为军服务创新项目(2020CZWJFW10).
Kidney stones and crystals in warship officers and soldiers: an epidemiological investigation
TANG Xiao-jing1,2,LIU Zi-yu1,XU Jin2,3,WU Da-xi2,4,LI Ting2,5,MAO Zhi-guo1*
(1. Department of Nephrology, The Second Affiliated Hospital of Naval Medical University (Second Military Medical University), Shanghai 200003, China;
2. Department of Internal Medicine, Medical Center of No. 91091 Troop of PLA, The Second Affiliated Hospital of Naval Medical University (Second Military Medical University), Sanya 572000, Hainan, China;
3. Department of Neurology, The Second Affiliated Hospital of Naval Medical University (Second Military Medical University), Shanghai 200003, China;
4. Department of Ultrasound, The Second Affiliated Hospital of Naval Medical University (Second Military Medical University), Shanghai 200003, China;
5. Department of Rheumatology, The Second Affiliated Hospital of Naval Medical University (Second Military Medical University), Shanghai 200003, China
*Corresponding author)
Abstract:
Objective To analyze the epidemiological characteristics and risk factors of kidney stones and crystals in warship officers and soldiers. Methods The original data of the physical examination report of officers and soldiers of a warship force in 2021 were collected, including general information, physical examination results, ultrasound, blood and urine test results, etc. In the meantime, the training environment and living habits were investigated. Then, the prevalence and risk factors of kidney stones and crystals of officers and soldiers were analyzed. Results Among the 1 315 officers and soldiers, the total prevalence of kidney stones and crystals was 6.92% (91/1 315). The prevalence of kidney stones and crystals increased with age, length of military service and length of on board (all P<0.01). Among the patients with kidney stones/crystals, 32.97% (30/91) were overweight, which was significantly higher than those without kidney stones/crystals (17.04%[204/1 197], P<0.01). The proportion of water intake more than 2 000 mL/d and the proportion of drinking milk in the kidney stone/crystal group were lower than those in the non-kidney stone/crystal group (20.45%[18/88] vs 30.24%[362/1 197], 82.95%[73/88] vs 90.64%[1 085/1 197], both P<0.05). There were no significant differences in the training environment, water source, beverages intake, serum uric acid level or urine osmotic pressure between the 2 groups (all P>0.05). Multivariate logistic regression analysis showed that older age and overweight were the independent risk factors for kidney stones/crystals in warship officers and soldiers, while water and milk intake were the protective factors (all P<0.05). Conclusion The prevalence of kidney stones and crystals in warship officers and soldiers is relatively high, which is related to older age, overweight and less water and milk intake.
Key words:  nephrolithiasis  epidemiology  prevalence  influencing factors  warship officers and soldiers