| 摘要: |
| 目的 分析子宫肌瘤剥除手术后非感染性发热的危险因素。方法 回顾性分析2021年1月至2022年1月在我院接受子宫肌瘤剥除手术的146例患者的临床资料。将术后48 h内体温≥38℃且无感染证据的发热定义为术后非感染性发热。采用单因素分析方法分析患者年龄、手术前后血红蛋白浓度、围术期抗生素使用、最大肌瘤大小、肌瘤数目、缝合方式、手术方式、术中是否穿透子宫内膜、是否同时行宫腔操作、手术时间等因素对术后非感染性发热的影响，将筛选的可疑危险因素进行多因素二分类logistic回归分析。结果 146例患者中发生术后非感染性发热者有25例，体温正常者121例。单因素分析结果显示，手术时间、手术方式、缝合方式、肌瘤数目、最大肌瘤大小、剖宫产史、术前及术后血红蛋白浓度、术后血红蛋白减少量、术后住院时间会影响术后非感染性发热的发生（P均＜0.05）。多因素logistic回归分析结果显示，手术时间（OR＝1.01，95% CI 1.00～1.02，P＝0.03）、手术方式（OR＝5.03，95% CI 1.74～14.56，P＜0.01）和肌瘤数目（OR＝1.33，95% CI 1.05～1.68，P＝0.02）是发生术后非感染性发热的独立危险因素（P均＜0.05）。结论 子宫肌瘤剥除术后发生术后非感染性发热的独立危险因素包括手术时间、手术方式和肌瘤数目，临床工作中应对这些因素进行干预。 |
| 关键词: 子宫肌瘤 腹腔镜手术 子宫肌瘤剥除术 发热 |
| DOI：10.16781/j.CN31-2187/R.20220238 |
| 投稿时间：2022-03-20修订日期：2022-04-29 |
| 基金项目: |
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| Risk factors of non-infectious fever after uterine myomectomy |
| GU Zhong-yi,SHEN Ji-zi,HU Yue,WEN Bi-wei,CHENG Guo-qing,GUAN Rui* |
(Department of Obstetrics and Gynaecology, The First Affiliated Hospital of Naval Medical University(Second Military Medical University), Shanghai 200433, China
*Corresponding author) |
| Abstract: |
| Objective To analyze the risk factors of non-infectious fever after uterine myomectomy. Methods The clinical data of 146 patients who underwent myomectomy in our hospital from Jan. 2021 to Jan. 2022 were retrospectively analyzed. Postoperative non-infectious fever refers to the body temperature≥38 ℃ within 48 h after operation, and there is no evidence of infection. Univariate analysis was used to analyze the influence of age, preoperative and postoperative hemoglobin concentration, perioperative antibiotic use, maximum size of myomas, number of myomas, suture mode, operation mode, whether to penetrate the endometrium during operation, whether to perform uterine cavity operation at the same time, operation time and other factors on postoperative non-infectious fever. Multivariate binary logistic regression analysis was performed on the selected suspected risk factors. Results Among the 146 patients, 25 had postoperative non-infectious fever and 121 had normal body temperature. Univariate analysis showed that operation time, operation mode, suture mode, number of myomas, maximum size of myomas, history of cesarean section, preoperative and postoperative hemoglobin concentration, preoperative and postoperative hemoglobin reduction and postoperative hospital stay would affect the postoperative non-infectious fever (all P＜0.05). The results of multivariate logistic regression analysis showed that the operation time (odds ratio ［OR］ ＝1.01, 95% confidence interval (CI) 1.00-1.02, P＝0.03), operation mode (OR＝5.03, 95% CI 1.74-14.56, P＜0.01) and the number of myomas (OR＝1.33, 95% CI 1.05-1.68, P＝0.02) were independent risk factors for the occurrence of postoperative non-infectious fever (all P＜0.05). Conclusion The independent risk factors of non-infectious fever after myomectomy include operation time, operation mode and number of myomas. These factors should be intervened in clinical work. |
| Key words: uterine fibroid laparoscopic surgery myomectomy fever |
