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剖宫产瘢痕妊娠发病机制的研究进展
王志明,严久琼,徐明娟*
0
(海军军医大学(第二军医大学)第一附属医院妇产科, 上海 200433
*通信作者)
摘要:
剖宫产瘢痕妊娠是一种特殊部位的异位妊娠,为剖宫产的远期并发症之一。若剖宫产瘢痕妊娠诊断不及时或误诊,可导致胎盘植入、子宫破裂和大出血等并发症的发生,严重时需切除子宫,甚至危及生命。近年来随着剖宫产率的上升和我国三孩政策的实施,有越来越多的女性再次妊娠时面临剖宫产瘢痕妊娠的风险。本文结合有关文献对剖宫产瘢痕妊娠的发病机制研究进行综述。
关键词:  剖宫产  剖宫产瘢痕妊娠  发病机制  切口愈合  滋养细胞
DOI:10.16781/j.CN31-2187/R.20220365
投稿时间:2022-05-01修订日期:2022-10-12
基金项目:海军军医大学(第二军医大学)第一附属医院“深蓝123重点攻关项目”(2020YSL009),海军军医大学(第二军医大学)第一附属医院“234学科攀峰计划”(2019YXK014).
Pathogenesis of cesarean scar pregnancy: research progress
WANG Zhi-ming,YAN Jiu-qiong,XU Ming-juan*
(Department of Obstetrics and Gynecology, The First Affiliated Hospital of Naval Medical University (Second Military Medical University), Shanghai 200433, China
*Corresponding author)
Abstract:
Cesarean scar pregnancy (CSP) is an ectopic pregnancy of special site, which is one of the long-term complications of cesarean section. If the diagnosis is delayed or misdiagnosed, it may lead to complications such as placental implantation, uterine rupture, massive bleeding, and in serious cases, hysterectomy, or even life-threatening events. In recent years, with the increase of cesarean section rate and the implementation of 3-child policy in China, more and more women face the risk of CSP when they get pregnant again. This paper reviews the pathogenesis of CSP based on relevant literatures.
Key words:  cesarean section  cesarean scar pregnancy  pathogenesis  wound healing  trophoblast cell