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无症状性颈动脉粥样硬化性狭窄治疗进展及脑卒中风险评估
葛曼悦1,杨鹏飞2,张磊2*
0
(1. 海军军医大学(第二军医大学)基础医学院学员一大队, 上海 200433;
2. 海军军医大学(第二军医大学)第一附属医院脑血管病中心, 上海 200433
*通信作者)
摘要:
无症状性颈动脉粥样硬化性狭窄是导致同侧缺血性脑血管事件的危险因素。但目前针对无症状性颈动脉粥样硬化性狭窄的医疗实践和临床证据之间存在矛盾,其最佳治疗方法仍有争议。因此,评估无症状性颈动脉粥样硬化性狭窄患者脑卒中发生风险,选择易损斑块进行外科干预以提高疗效是必要的。本文回顾了无症状性颈动脉粥样硬化性狭窄的流行病学、治疗方法及脑卒中风险评估和潜在干预指征的最新成果,旨在减少不必要的干预,更加有效地预防脑卒中。
关键词:  颈动脉  动脉粥样硬化  颈动脉狭窄  脑卒中
DOI:10.16781/j.CN31-2187/R.20230157
投稿时间:2023-03-31修订日期:2023-10-10
基金项目:国家自然科学基金(8237051064).
Treatment progress and stroke risk assessment of asymptomatic carotid atherosclerotic stenosis
GE Manyue1,YANG Pengfei2,ZHANG Lei2*
(1. The First Student Team, College of Basic Medical Sciences, Naval Medical University(Second Military Medical University), Shanghai 200433, China;
2. Neurovascular Center, The First Affiliated Hospital of Naval Medical University(Second Military Medical University), Shanghai 200433, China
*Corresponding author)
Abstract:
Asymptomatic carotid atherosclerotic stenosis is a risk factor of ipsilateral ischemic cerebrovascular events. However, the treatments for asymptomatic carotid atherosclerotic stenosis are still controversial, for the medical practice contradicts with the clinical evidence. Hence, it is necessary to access the stroke risk of asymptomatic carotid atherosclerotic stenosis patients and choose vulnerable plaques for surgical intervention to improve the effectiveness of treatment. This review briefly summarizes the epidemiology and research progress on the treatment, stroke risk assessment and underlying intervention indications of asymptomatic carotid atherosclerotic stenosis, aiming to reduce unnecessary interventions and prevent stroke more effectively.
Key words:  carotid artery  atherosclerosis  carotid artery stenosis  stroke