| 摘要: |
| 目的 探讨40 m高压空气暴露对潜水员肱动脉功能的影响。方法 选择5名潜水员作为受试者。所有受试者均接受最高压力为40 m的高压空气暴露，高气压暴露时间共计190 min。采用多普勒超声诊断仪检测高气压暴露前后受试者的肱动脉直径、收缩峰值流速（SPV）、阻力指数（RI），计算血流介导的血管舒张（FMD），评价高气压暴露对肱动脉功能的影响。结果 与高气压暴露前相比，高气压暴露后肱动脉直径呈下降趋势（P＞0.05），RI和FMD稍有升高（P＞0.05），而SPV下降（P＜0.05）。结论 40 m高压空气暴露可导致肱动脉收缩，血流阻力增加、流速下降，但对肱动脉的功能影响较小，FMD变化不显著。 |
| 关键词: 潜水员 血流介导的血管舒张 血管内皮细胞 肱动脉 超声检查 |
| DOI：10.16781/j.CN31-2187/R.20230409 |
| 投稿时间：2023-07-21修订日期：2023-10-10 |
| 基金项目:上海市市级科技重大项目（2023SHZDZX02-030702）. |
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| Effect of 40 m hyperbaric air exposure on brachial artery function of divers |
| LIU Wenwu1,ZHANG Tingting1,WEN Yukun1,YU Xuhua1,XU Jiajun1,WANG Shifeng2* |
(1. Department of Diving and Hyperbaric Medical Research, Naval Medical Center, Naval Medical University (Second Military Medical University), Shanghai 200433, China;
2. Department of Research, Naval Medical Center, Naval Medical University (Second Military Medical University), Shanghai 200433, China
*Corresponding author) |
| Abstract: |
| Objective To investigate the effect of 40 m hyperbaric air exposure on brachial artery function of divers. Methods Five divers were enrolled and exposed to hyperbaric air with a maximum pressure of 40 m for a total of 190 min. The brachial artery diameter, systolic peak velocity (SPV) and resistance index (RI) were measured by Doppler ultrasonography before and after hyperbaric air exposure, and flow-mediated dilation (FMD) was calculated to evaluate the effect of hyperbaric air exposure on brachial artery function. Results Compared with before hyperbaric air exposure, the brachial artery diameter was decreased (P＞0.05), RI and FMD were increased slightly (P＞0.05), while SPV was decreased significantly (P＜0.05) after hyperbaric air exposure. Conclusion Exposure to hyperbaric air at 40 m can lead to brachial artery contraction, increase resistance, and decrease flow velocity, but it has a slight impact on the brachial artery function, with no significant change in FMD. |
| Key words: diver flow-mediated dilation vascular endothelial cells brachial artery ultrasonography |
