| 摘要: |
| 随着多模态医学影像技术的智能化发展，超声等影像诊断技术逐渐被用于甲状腺弥漫性病变结构与功能的定量评估。本文主要综述了常规超声技术（如二维灰阶、多普勒超声）、新型超声技术（如超微血管成像、三维超声、超声弹性成像、超声造影）及其他影像学诊断技术（如CT、MRI、放射性核素显像等）在甲状腺弥漫性病变定量诊断中的研究现状及进展。多模态超声影像技术可弥补单一诊断手段的不足，对甲状腺弥漫性病变结构与功能的定量评估打破了既往主要依靠超声医师主观判断和定性诊断的局限性，有利于全面综合定量诊断甲状腺弥漫性疾病，指导临床个体化诊疗。 |
| 关键词: 甲状腺弥漫性病变 定量诊断 超声检查 智能影像 |
| DOI：10.16781/j.CN31-2187/R.20220515 |
| 投稿时间：2022-06-17修订日期：2022-11-14 |
| 基金项目:国家自然科学基金（81501492），上海市自然科学基金（20ZR1457900），上海市虹口区卫生健康委员会医学科研课题面上项目（虹卫2302-26），上海市虹口区卫生健康委员会临床重点扶持专科建设项目（HKLCFC202404），海军军医大学（第二军医大学）第二附属医院人才建设三年行动计划——“金字塔人才工程”军事医学人才项目（1009），同济大学附属上海市第四人民医院科研启动专项（SYKYQD06101），同济大学附属上海市第四人民医院学科助推计划临床研究重点项目（SY-XKZT-2023-2002）. |
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| Ultrasound imaging quantitative diagnostic techniques for diffuse thyroid diseases: research progress |
| HUANG Jing1,ZHAO Jiaqi1,2* |
(1. Department of Ultrasound, The Second Affiliated Hospital of Naval Medical University (Second Military Medical University), Shanghai 200003, China;
2. Department of Ultrasound, Shanghai Fourth People's Hospital Affiliated to Tongji University, Shanghai 200434, China
* Corresponding author) |
| Abstract: |
| With the intelligent development of multimodal medical imaging technology, ultrasound and other diagnostic imaging techniques are increasingly used for quantitative structural and functional assessment of diffuse thyroid diseases. In this paper, the research status and progress of ultrasound imaging quantitative diagnostic techniques for diffuse thyroid lesions were reviewed, including conventional ultrasound techniques (such as 2-dimensional gray-scale and Doppler ultrasound), new ultrasound techniques (such as superb microvascular imaging, 3-dimensional ultrasound, ultrasound elastography, and contrast enhanced ultrasound), and other diagnostic imaging techniques (such as computed tomography, magnetic resonance imaging, and radionuclide imaging). By combining multimodal ultrasound imaging techniques, the limitations of single diagnostic means can be overcome, and the quantitative assessment of the structure and function of diffuse thyroid diseases can reduce the limitations of previous subjective and qualitative diagnoses. Comprehensive analysis and quantitative diagnosis of diffuse thyroid diseases can guide the individualized clinical diagnosis and treatment. |
| Key words: diffuse thyroid diseases quantitative diagnosis ultrasonography intelligent imaging |
