| 摘要: |
| 目的：探讨血液AFP mRNA在复发性肝癌及伴有肝外远处器官转移的原发性肝癌中的表达及意义。方法：应用巢式RT-PCR检测40例复发性肝癌及伴有肝外远处器官转移的原发性肝癌血液AFP mRNA。结果：21例伴有肝外远处器官转移的原发性肝癌血液AFP mRNA均表达阳性（100％），19例复发性肝癌患者中有7例血液AFP mRNA表达阳性（36.8％)，两组比较差异有显著性意义(P<0.01）。结论：血液AFP mRNA有希望成为判断肝癌复发或预测肝癌远处器官转移的客观性指标之一。 |
| 关键词: 肝细胞瘤、RNA，信使、甲胎蛋白类 |
| DOI： |
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| 基金项目: |
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| The role of blood AFP mRNA in patients with recurrent or distant metastasis of hepatocellular cacinoma |
| 黄长辉,傅继梁,陈汉,张柏和,钱光相,吴孟超,刘扬 |
| () |
| Abstract: |
| Objective: To study the expression of blood AFP mRNA in patients with recurrent or distant metastasis of human hepatocellular cacinoma (HCC). Methods: We examined 40 blood samples from patients with recurrent or distant metastasis HCC by nested RT-PCR to find out AFP mRNA. Results: AFP mRNA was detected in 7 blood samples from 19 HCC with recurrent HCC (36.8%) and in all HCC patients with distant metastasis(100%). Conclusions: AFP mRNA may be used as a marker of HCC recurrent and metastasis. |
| Key words: hepatoma RNA, messenger alpha fetoproteins |
