| 摘要: |
| 目的：探讨2型糖尿病患者血清晚期糖化终产物(AGE)浓度。方法：采用ELISA法检测2型糖尿病患者及正常人血清AGE含量。结果：15例无糖尿病慢性并发症和11例有糖尿病慢性并发症的患者血清AGE/蛋白分别为0.597±0.540和0.750±0.390,均显著高于正常人(P＜0.01)。结论：糖尿病患者血清AGE水平较正常人明显上升；血清AGE水平可以作为糖尿病血糖控制和糖尿病慢性并发症监测的参考指标。 |
| 关键词: 糖化终产物 糖尿病 |
| DOI： |
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| 基金项目: |
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| The concentration of serum AGE and its clinical significance in diabetic patients |
| 黄勤,邹大进,赵庆 |
| () |
| Abstract: |
| Objective：To evaluate the relationship between serum AGE and diabetic chronic complication (DCC). Methods: Serum AGE in diabetic patients was measured by competitive ELISA. Results: Both of 15 diabetic patients with DCC and 11 diabetic patients without DCC had higher mean serum AGE concentrations than that of normal group (P＜0.01). Conclusion: This may be the increasing production of endogenous AGE that the diabetic group had a higher mean serum AGE than normal group,serum AGE may provide an indicators of long term blood glucose control and predict the occurances of diabetic chronic complications. |
| Key words: glycation end products diabetes mellitus |
