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| 结肠镜对家族性腺瘤性息肉病家系成员筛选的意义 |
| 于恩达,徐晓东,孟荣贵,傅传刚,徐洪莲,YUEn-da,XUXiao-dong,MENGRong-gui,FUChuan-gang,XUHong-lian |
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| 摘要: |
| 目的:探讨结肠镜对家族性腺瘤性息肉病家系成员筛选的价值.方法:回顾我科1985～2002年通过结肠镜对23个家族性腺瘤性息肉病患者家系共38例亲属进行筛选,观察息肉的量、形态、分布以及病理等特征,分析结肠镜对家系亲属筛选的作用.结果:38例对象中发现有16例大肠内有息肉生长,筛选阳性率达42.1％;1例腺瘤呈重度不典型增生,占6.3％;左半结肠、直肠内息肉分布密集.结论:结肠镜是家族性腺瘤性息肉病家系成员筛选安全、可靠的方法. |
| 关键词: 腺瘤息肉病,结肠、结肠镜检查、筛选 |
| DOI：10.3724/SP.J.1008.2006.00362 |
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| Significance of colonoscopy in screening of family members from familial adenomatous polyposis families |
| 于恩达,徐晓东,孟荣贵,傅传刚,徐洪莲,YU En-da,XU Xiao-dong,MENG Rong-gui,FU Chuan-gang,XU Hong-lian |
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| Abstract: |
| Objective：To study the diagnostic value of colonoscopy in screening of family members of a familial adenomatous polyposis （FAP） family. Methods： The colonoscopic findings of 38 sibs from 23 FAP families （1985-2002） were retrospectively studied. The diagnostic value of colonoscopy for screening FAP in FAP families was analyzed through determining the amount, morphology, and pathology of polyps. Results： Sixteen of the 38 sibs were found to have polypous growths, the positive screening rate being 42.1% ; of the 16 cases of polypous growths, one was found to be severe atypical proliferation. The left hemicolon and rectum had dense polyps. Conclusion： Colonoscopy is a safe and reliable screening examination in sibs of FAP families. |
| Key words: adenomatous polyposis coli colonoscopy screening |
