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随机对照试验及统计学分析在临床医学应用中存在的问题
贺佳
0
(第二军医大学卫生勤务学系卫生统计学教研室,上海,200433)
摘要:
随机对照试验(RCT)研究被认为是临床治疗试验中论证强度最高的试验方法,可为临床实践提供真实的科学依据,引导临床医师在实践中做出正确的决策.本文介绍了RCT的方法及设计原则,分析了在临床实际应用中存在的问题,并对RCT中统计学方法应用的常见错误进行了分析,阐述了应用RCT及采用正确的统计学分析方法的重要性.
关键词:  随机对照试验、统计学,医学、临床医学
DOI:10.3724/SP.J.1008.2006.00697
投稿时间:2006-06-26修订日期:2006-06-29
基金项目:
Randomized controlled trial and statistical analysis methods for clinical medicine: the existing problems
HE Jia
()
Abstract:
Randomized controlled trial (RCT), considered as the strongest evidence-based method in clinical trial, can provide first-hand scientific evidence for clinical practice and instruct clinicians to make correct decisions in practice. This article introduces the principles for RCT designing, analyzes the common problems concerning RCT in clinical practice and the common mistakes made in RCT statistical methods. It is concluded that application of RCT method and correct statistical methods are of great importance in clinical medical research.
Key words:  randomized controlled trials  statistics, medical  clinical medicine