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用于战时调节飞行人员睡眠与抗疲劳的精神类药物
张娴1,2,邹豪1,高申1*
0
(1.第二军医大学药学院药剂学教研室,上海 200433;2.解放军第451医院药剂科,西安 710054)
摘要:
精神药物,包括中枢兴奋药与中枢抑制药,对现代军事斗争中军人的心理状态有深远的影响。本文综述了精神药物的代谢动力学特点及其作用机制与使用效果,并对精神药物在战时(伊拉克战争、英阿马岛战争、美军空袭利比亚和海湾战争) 调节飞行人员睡眠与抗疲劳中的应用进行了综述,同时对战时合理使用精神药物提出建议。
关键词:  军事精神病学  中枢神经系统刺激药  中枢神经系统抑制药  睡眠  抗疲劳
DOI:10.3724/SP.J.1008.2008.00841
投稿时间:2007-02-07修订日期:2008-06-19
基金项目:
Pychotropic drugs for sleep regulation and anti-fatigue in aircrew members during wartime
ZHANG Xian1,2,ZOU Hao1,GAO Shen1*
(1.Department of Pharmaceutics,School of Pharmacy,Second Military Medical University,Shanghai 200433,China;2.Department of Medicine,No.451 Hospital of PLA,Xi’an 710054)
Abstract:
In modern war,psychotropic drugs,including central stimulants and central depressants,have profound influence on the mental states of soldiers.This paper reviews the pharmacokinetics,pharmacological mechanisms and efficacy of psychotropic drugs;and also introduces the application of psychotropic drugs for sleep regulation and anti-fatigue in aircrew members during Iraqi war,South Atlantic Campaign,Libyan Air Strike and Gulf War.Suggestions are given on proper use of psychotropic drugs in wartime.
Key words:  military psychiatry  central nervous system stimulants  central nervous system depressants  sleep  anti-fatigue