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肥厚型心肌病患者左室心肌收缩期应变率的速度向量成像定量分析
江鸿*,,智光,阎国辉,侯海军,周肖,徐勇
0
(解放军军医进修学院,北京 100000)
摘要:
目的:应用速度向量成像(VVI)技术,探讨肥厚型心肌病(HCM)患者左室心肌收缩期应变(ε)、应变率(SR)的改变。方法:选取20例室间隔肥厚的HCM患者和20例年龄配对的健康志愿者,在VVI模式下,分别取心尖四腔、三腔和二腔切面,分析左室18个室壁节段的ε和SR曲线,测量收缩期峰值。结果:对照组左室心肌收缩期SR值为(-1.06±0.09)/s,HCM组为(-0.74±0.16)/s,HCM组左室心肌各节段收缩期SR较对照组明显减低,差异有统计学意义(P<0.05)。HCM组各节段收缩期SR减低不仅仅限于肥厚部位,也存在于非肥厚部位。结论:HCM患者左室心肌收缩期ε和SR明显低于对照组,HCM患者收缩期ε和SR的减低不仅限于肥厚部位。
关键词:  肥厚型心肌病  速度向量成像  应变  应变率;左心室;心肌收缩期
DOI:10.3724/SP.J.1008.2008.00390
投稿时间:2007-10-15修订日期:2008-03-11
基金项目:
Quantitative analysis of left ventricular systolic strain and strain rate in hypertrophic cardiomyopathy patients by velocity vector imaging
JIANG Hong*,ZHI Guang,YAN Guo-hui,HOU Hai-jun,ZHOU Xiao,XU Yong
(PLA Postgraduate Medical School,Beijing 10000,China)
Abstract:
Objective:To observe the changes of left ventricular (LV) systolic strain(ε) and strain rate(SR) in patients with hypertrophic cardiomyopathy (HCM) and normal healthy subjects by velocity vector imaging(VVI).Methods: Twenty patients with HCM and 20 age-matched healthy adults were enrolled in this study. The peak systolic ε , SR of 18 segments in the 4, 3 and 2-chamber views were measured by VVI. Results: It was found that the systolic SR was (-1.06±0.09)/s in the healthy control group and (-0.74±0.16)/s in the HCM group(P<0.05). The reduction of systolic SR in HCM group was found not only at the hypertrophic regions but also at normal regions. Conclusion: The systolic ε and SR in HCM group is lower than that in the normal control group. The reduction of systolic ε and SR in HCM group is not limited to the hypertrophic region.
Key words:  hypertrophic cardiomyopathy  velocity vector imaging  strain  strain rate  left ventricle  systole